Tissue-specific early and late activated lymphocytes immunophenotype in chronic rhinosinusitis with nasal polyps
Key pointsT-cell activation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is enriched by late cytotoxic T cells.The proportion of early and intermediate activated cytotoxic T cells decreases in nasal polyps of patients with CRSwNP.Our results identify late activated cytotoxic T...
| Autores: | , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) |
| Repositorio: | r-FISABIO. Repositorio Institucional de Producción Científica |
| OAI Identifier: | oai:fisabio.fundanetsuite.com:p16527 |
| Acceso en línea: | https://fisabio.portalinvestigacion.com/publicaciones/16527 |
| Access Level: | acceso abierto |
| Palabra clave: | allergic rhinitis asthma biomarker chronic disease chronic rhinosinusitis quality of life SNOT-22 |
| Sumario: | Key pointsT-cell activation in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is enriched by late cytotoxic T cells.The proportion of early and intermediate activated cytotoxic T cells decreases in nasal polyps of patients with CRSwNP.Our results identify late activated cytotoxic T cells as potential biomarkers or therapeutic targets for patients with CRSwNP. |
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