Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out

Despite wide antiretroviral scale-up during the past two decades resulting in declining new infections and mortality globally, HIV-associated tuberculosis remains as a major public health concern. Tuberculosis is the leading HIV-associated opportunistic infection and the main cause of death globally...

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Autores: Letang, Emilio, Ellis, Jayne, Naidoo, Kogieleum, Casas, Esther C., Sánchez, Paquita, Hassan-Moosa, Razia, Cresswell, Fiona, Miró Meda, José M. (José María), 1956-, García-Basteiro, Alberto L.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/168021
Acceso en línea:https://hdl.handle.net/2445/168021
Access Level:acceso abierto
Palabra clave:Tuberculosi
VIH (Virus)
Antiretrovirals
Tuberculosis
HIV (Viruses)
Antiretroviral agents
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spelling Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-outLetang, EmilioEllis, JayneNaidoo, KogieleumCasas, Esther C.Sánchez, PaquitaHassan-Moosa, RaziaCresswell, FionaMiró Meda, José M. (José María), 1956-García-Basteiro, Alberto L.TuberculosiVIH (Virus)AntiretroviralsTuberculosisHIV (Viruses)Antiretroviral agentsDespite wide antiretroviral scale-up during the past two decades resulting in declining new infections and mortality globally, HIV-associated tuberculosis remains as a major public health concern. Tuberculosis is the leading HIV-associated opportunistic infection and the main cause of death globally and, particularly, in resource-limited settings. Several challenges exist regarding diagnosis, global implementation of latent tuberculosis treatment, management of active tuberculosis, delivery of optimal patient-centered TB and HIV prevention and care in high burden countries. In this article we review the advances on pathogenesis, diagnosis, and treatment after nearly two decades of global roll-out of antiretroviral therapy and discuss the current challenges for the global control of tuberculosis-HIV co-infection.Elsevier2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfhttps://hdl.handle.net/2445/168021Articles publicats en revistes (Medicina)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésVersió postprint del document publicat a: https://doi.org/10.1016/j.arbres.2019.11.015Archivos de Bronconeumologia, 2020, vol. 56, num. 7, p. 446-454https://doi.org/10.1016/j.arbres.2019.11.015cc-by-nc-nd (c) Elsevier, 2020http://creativecommons.org/licenses/by-nc-nd/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1680212026-05-27T06:46:51Z
dc.title.none.fl_str_mv Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
title Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
spellingShingle Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
Letang, Emilio
Tuberculosi
VIH (Virus)
Antiretrovirals
Tuberculosis
HIV (Viruses)
Antiretroviral agents
title_short Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
title_full Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
title_fullStr Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
title_full_unstemmed Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
title_sort Tuberculosis-HIV co-infection: Progress and challenges after two decades of global antiretroviral treatment roll-out
dc.creator.none.fl_str_mv Letang, Emilio
Ellis, Jayne
Naidoo, Kogieleum
Casas, Esther C.
Sánchez, Paquita
Hassan-Moosa, Razia
Cresswell, Fiona
Miró Meda, José M. (José María), 1956-
García-Basteiro, Alberto L.
author Letang, Emilio
author_facet Letang, Emilio
Ellis, Jayne
Naidoo, Kogieleum
Casas, Esther C.
Sánchez, Paquita
Hassan-Moosa, Razia
Cresswell, Fiona
Miró Meda, José M. (José María), 1956-
García-Basteiro, Alberto L.
author_role author
author2 Ellis, Jayne
Naidoo, Kogieleum
Casas, Esther C.
Sánchez, Paquita
Hassan-Moosa, Razia
Cresswell, Fiona
Miró Meda, José M. (José María), 1956-
García-Basteiro, Alberto L.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Tuberculosi
VIH (Virus)
Antiretrovirals
Tuberculosis
HIV (Viruses)
Antiretroviral agents
topic Tuberculosi
VIH (Virus)
Antiretrovirals
Tuberculosis
HIV (Viruses)
Antiretroviral agents
description Despite wide antiretroviral scale-up during the past two decades resulting in declining new infections and mortality globally, HIV-associated tuberculosis remains as a major public health concern. Tuberculosis is the leading HIV-associated opportunistic infection and the main cause of death globally and, particularly, in resource-limited settings. Several challenges exist regarding diagnosis, global implementation of latent tuberculosis treatment, management of active tuberculosis, delivery of optimal patient-centered TB and HIV prevention and care in high burden countries. In this article we review the advances on pathogenesis, diagnosis, and treatment after nearly two decades of global roll-out of antiretroviral therapy and discuss the current challenges for the global control of tuberculosis-HIV co-infection.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/168021
url https://hdl.handle.net/2445/168021
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1016/j.arbres.2019.11.015
Archivos de Bronconeumologia, 2020, vol. 56, num. 7, p. 446-454
https://doi.org/10.1016/j.arbres.2019.11.015
dc.rights.none.fl_str_mv cc-by-nc-nd (c) Elsevier, 2020
http://creativecommons.org/licenses/by-nc-nd/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by-nc-nd (c) Elsevier, 2020
http://creativecommons.org/licenses/by-nc-nd/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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