PEGylated opto-magnetic gold and silver sulfide iron oxide nanoprobes for synergistic photothermal therapy
There is a continuous vivid search for biocompatible hybrid magneto-optical nanoprobes with high heating and photoluminescence efficiencies for photothermal theranostics. Herein, two tailored multipurpose hybrid PEGylated gold (Au) and silver sulfide (Ag2S) magnetic iron oxide nanoparticle formulati...
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Universidad Autónoma de Madrid |
| Repositorio: | Biblos-e Archivo. Repositorio Institucional de la UAM |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.uam.es:10486/718280 |
| Acceso en línea: | http://hdl.handle.net/10486/718280 https://dx.doi.org/10.1021/acsanm.4c02889 |
| Access Level: | acceso abierto |
| Palabra clave: | AMF gold (Au) NPs laser magnetic hyperthermia magnetic iron oxide nanoparticles (NPs) near infrared (NIR) photothermal therapy silver sulfide (Ag2S) NPs Física |
| Sumario: | There is a continuous vivid search for biocompatible hybrid magneto-optical nanoprobes with high heating and photoluminescence efficiencies for photothermal theranostics. Herein, two tailored multipurpose hybrid PEGylated gold (Au) and silver sulfide (Ag2S) magnetic iron oxide nanoparticle formulations (Au-PEG-MNPs and Ag2S-PEG-MNPs) with unique opto-magnetic properties for simultaneous photothermal therapy were prepared. The physiochemical properties of the hybrid MNPs were fully characterized using various electronic and spectroscopic techniques, showing colloidal stabilized small-sized nanoparticles (core sizes = 10 nm, DH = 200 nm) with high saturation magnetizations (Ms up to 85 emu/g) and superparamagnetic behavior. Thermal effects in response to an alternating magnetic field (AMF) at different frequencies (f = 25-300 kHz) and field intensities (H = 12 and 24 kA/m) were assessed using an ultrafast magnetometric method, revealing high heating efficiencies with distinctive heating responses. The “optother |
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