Catalytic Hydrophosphorylation of Propiolates and Three-Component Phosphorylation of Aldehydes

A practical and efficient regio- and stereoselective hydrophosphorylation of propiolates, as well as a multicomponent reaction incorporating an aldehyde component, is reported. Both processes proceed with atom economy in very straightforward experimental procedures. The reactions are catalyzed by DA...

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Detalles Bibliográficos
Autores: Tejedor, David, Carrillo Fumero, Romen, Samuel Delgado-Hernández, Alejandro Peixoto de Abreu Lima, Eva María Martín Díaz, Jimena Scoccia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/417913
Acceso en línea:http://hdl.handle.net/10261/417913
Access Level:acceso abierto
Palabra clave:Aldehydes
Alkyls
Catalysts
Hydrocarbons
Organophosphorus compounds
Descripción
Sumario:A practical and efficient regio- and stereoselective hydrophosphorylation of propiolates, as well as a multicomponent reaction incorporating an aldehyde component, is reported. Both processes proceed with atom economy in very straightforward experimental procedures. The reactions are catalyzed by DABCO (1,4-diazabicyclo[2.2.2]octane) and use readily available H-phosphonates as the phosphorylating agent.