Cardiogenic Shock Complicating Takotsubo Syndrome

BACKGROUND: Sex-related differences in Takotsubo syndrome have been described, but no information is available in patients who develop cardiogenic shock. METHODS AND RESULTS: Of 412 patients with Takotsubo syndrome with cardiogenic shock, 71 (17.2%) were men. Male patients were older (71.1±12.2 vers...

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Detalhes bibliográficos
Autores: Martínez-Sellés, Manuel|||0000-0003-0289-6229, Vedia Cruz, Oscar|||0000-0001-5062-3335, Corbí-Pascual, Miguel|||0000-0001-5923-1290, Salamanca, Jorge|||0000-0002-5067-5052, Blanco, Emilia|||0000-0001-6157-679X, Fernández-Cordon, Clara|||0000-0002-2492-2873, Almendro-Delia, Manuel|||0000-0001-7144-4782, Pérez-Castellanos, Alberto|||0000-0002-5879-0012, Martin-Garcia, Agustin C.|||0000-0001-8662-3791, Duran Cambra, Albert|||0000-0002-5692-6844, Becerra-Muñoz, Víctor Manuel|||0000-0001-6454-7644, Guillén Marzo, Marta|||0000-0003-3345-2356, Uribarri, Aitor|||0000-0002-6911-7480, Tomasino, Marco|||0000-0003-1989-4342, Núñez Gil, Iván J., Vila-Sanjuán, Sofía, Vazirani Ballesteros, Ravi|||0000-0002-7337-0593
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:324384
Acesso em linha:https://ddd.uab.cat/record/324384
https://dx.doi.org/urn:doi:10.1161/JAHA.124.036800
Access Level:acceso abierto
Palavra-chave:Takotsubo
cardiogenic shock
heart failure
prognosis
Sexisme en l'educació
Descrição
Resumo:BACKGROUND: Sex-related differences in Takotsubo syndrome have been described, but no information is available in patients who develop cardiogenic shock. METHODS AND RESULTS: Of 412 patients with Takotsubo syndrome with cardiogenic shock, 71 (17.2%) were men. Male patients were older (71.1±12.2 versus 65.3±17.1 years, P<0.001), more frequently smokers (47 [66.2%] versus 66 [19.4%], P<0.01), with higher prevalence of neoplasms (6 [8.5%] versus 8 [2.3%], P=0.01), lower left ventricular ejection fraction (31% versus 37%, P<0.001), more frequent invasive mechanical ventilation (30 [42.3%] versus 90 [26.4%], P=<0.01), higher rate of infections (43 [60.6%] versus 148 [43.4%], P=<0.01), and longer in-hospital stay (19±20 days versus 13±15 days, P=0.02). A total of 55 patients (13.3%) died during hospital admission, and 90 patients (21.8%) died at the end of the 5-year follow-up. Male sex was not significantly associated with the in-hospital (odds ratio, 1.31 [95% CI, 0.64-2.68]) or 5-year mortality rate (hazard ratio, 1.66 [95% CI, 0.93-2.94]). In the matched cohort, no significant differences in the short-and long-term mortality rate were found either. CONCLUSIONS: Cardiogenic shock due to Takotsubo syndrome has high short-and long-term mortality rates that are similar in men and women.

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