Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak

The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of...

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Autores: Guerrero-Vadillo, María, Peñuelas, Marina, Domínguez, Angela, Godoy, Pere, Gomez-Barroso, Diana, Soldevila, Núria, Izquierdo, Conchita, Martínez, Ana, Torner, Núria, Avellón, Ana, Rius, Cristina, Varela Martinez, Maria del Carmen
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/15851
Acceso en línea:http://hdl.handle.net/20.500.12105/15851
Access Level:acceso abierto
Palabra clave:Hepatitis A
Adolescent
Adult
Female
Humans
Male
Young Adult
Disease Outbreaks
Homosexuality, Male
Spain
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network_acronym_str ES
network_name_str España
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spelling Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European OutbreakGuerrero-Vadillo, MaríaPeñuelas, MarinaDomínguez, AngelaGodoy, PereGomez-Barroso, DianaSoldevila, NúriaIzquierdo, ConchitaMartínez, AnaTorner, NúriaAvellón, AnaRius, CristinaVarela Martinez, Maria del CarmenHepatitis AAdolescentAdultFemaleHumansMaleYoung AdultDisease OutbreaksHomosexuality, MaleSpainThe aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016-2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space-time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15-44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space-time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging.Multidisciplinary Digital Publishing Institute (MDPI)Centro de Investigación Biomédica en Red - CIBERESP (Epidemiología y Salud Pública)Instituto de Salud Carlos III20232023-04-1920222022-12-1420222022-12-14research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/20.500.12105/15851reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/158512026-06-12T12:43:37Z
dc.title.none.fl_str_mv Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
spellingShingle Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
Guerrero-Vadillo, María
Hepatitis A
Adolescent
Adult
Female
Humans
Male
Young Adult
Disease Outbreaks
Homosexuality, Male
Spain
title_short Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_full Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_fullStr Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_full_unstemmed Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
title_sort Epidemiological Characteristics and Spatio-Temporal Distribution of Hepatitis A in Spain in the Context of the 2016/2017 European Outbreak
dc.creator.none.fl_str_mv Guerrero-Vadillo, María
Peñuelas, Marina
Domínguez, Angela
Godoy, Pere
Gomez-Barroso, Diana
Soldevila, Núria
Izquierdo, Conchita
Martínez, Ana
Torner, Núria
Avellón, Ana
Rius, Cristina
Varela Martinez, Maria del Carmen
author Guerrero-Vadillo, María
author_facet Guerrero-Vadillo, María
Peñuelas, Marina
Domínguez, Angela
Godoy, Pere
Gomez-Barroso, Diana
Soldevila, Núria
Izquierdo, Conchita
Martínez, Ana
Torner, Núria
Avellón, Ana
Rius, Cristina
Varela Martinez, Maria del Carmen
author_role author
author2 Peñuelas, Marina
Domínguez, Angela
Godoy, Pere
Gomez-Barroso, Diana
Soldevila, Núria
Izquierdo, Conchita
Martínez, Ana
Torner, Núria
Avellón, Ana
Rius, Cristina
Varela Martinez, Maria del Carmen
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Centro de Investigación Biomédica en Red - CIBERESP (Epidemiología y Salud Pública)
Instituto de Salud Carlos III
dc.subject.none.fl_str_mv Hepatitis A
Adolescent
Adult
Female
Humans
Male
Young Adult
Disease Outbreaks
Homosexuality, Male
Spain
topic Hepatitis A
Adolescent
Adult
Female
Humans
Male
Young Adult
Disease Outbreaks
Homosexuality, Male
Spain
description The aim of our study was to describe the results of the epidemiological surveillance of hepatitis A infections in Spain in the context of the 2016/2017 European outbreak, particularly of hepatitis A outbreaks reported in the MSM population, incorporating the results of a spatio-temporal analysis of cases. Hepatitis A cases and outbreaks reported in 2016-2017 to the National Epidemiological Surveillance Network were reviewed: outbreaks in which some of the cases belonged to the MSM group were described, and clusters of hepatitis A cases in men and women were analysed using a space-time scan statistic. Twenty-six outbreaks were identified, with a median size of two cases per outbreak, with most of the outbreak-related cases belonging to the 15-44 years-old group. Nearly 85% occurred in a household setting, and in all outbreaks, the mode of transmission was direct person-to-person contact. Regarding space-time analysis, twenty statistically significant clusters were identified in the male population and eight in the female population; clusters in men presented a higher number of observed cases and affected municipalities, as well as a higher percentage of municipalities classified as large urban areas. The elevated number of cases detected in clusters of men indicates that the number of MSM-related outbreaks may be higher than reported, showing that spatio-temporal analysis is a complementary, useful tool which may improve the detection of outbreaks in settings where epidemiological investigation may be more challenging.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-12-14
2022
2022-12-14
2023
2023-04-19
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/15851
url http://hdl.handle.net/20.500.12105/15851
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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