Neuroimaging in attention-deficit/hyperactivity disorder

Purpose of review: Neuroimaging research on attention-deficit/hyperactivity disorder (ADHD) continues growing in extent and complexity, although it has yet to become clinically meaningful. We review recent MRI research on ADHD, to identify robust findings, current trends and challenges. Recent findi...

Descripción completa

Detalles Bibliográficos
Autores: Pereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949d, Castellanos, F.X. (Francisco X.)|||/items/96b377d4-821d-4950-bfb2-6d22cc924eba
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/116321
Acceso en línea:https://hdl.handle.net/10171/116321
Access Level:acceso abierto
Palabra clave:Attention-deficit/hyperactivity disorder
MRI
Neuroimaging
Personalized medicine
id ES_86fd8dadc3eda275e49aa396e80da086
oai_identifier_str oai:dadun.unav.edu:10171/116321
network_acronym_str ES
network_name_str España
repository_id_str
spelling Neuroimaging in attention-deficit/hyperactivity disorderPereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949dCastellanos, F.X. (Francisco X.)|||/items/96b377d4-821d-4950-bfb2-6d22cc924ebaAttention-deficit/hyperactivity disorderMRINeuroimagingPersonalized medicinePurpose of review: Neuroimaging research on attention-deficit/hyperactivity disorder (ADHD) continues growing in extent and complexity, although it has yet to become clinically meaningful. We review recent MRI research on ADHD, to identify robust findings, current trends and challenges. Recent findings: We identified 40 publications between January 2019 and September 2020 reporting or reviewing MRI research on ADHD. Four meta-analyses have presented conflicting results regarding across-study convergence of functional and resting-state functional (fMRI and R-fMRI) studies on ADHD. On the other hand, the Enhancing NeuroImaging Genetics Through Meta-Analysis international consortium has identified statistically robust albeit small differences in structural brain cortical and subcortical indices in children with ADHD versus typically developing controls. Other international consortia are harnessing open-science efforts and multimodal data (imaging, genetics, phenotypic) to shed light on the complex interplay of genetics, environment, and development in the pathophysiology of ADHD. We note growing research in 'prediction' science, which applies machine-learning analysis to identify biomarkers of disease based on big data. Summary: Neuroimaging in ADHD is still far from informing clinical practice. Current large-scale, multimodal, and open-science initiatives represent promising paths toward untangling the neurobiology of ADHD.Wolters Kluwer Health, Inc.Dadun. Depósito Académico Digital Universidad de Navarra20212021-01-0120212021-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/116321reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/1163212026-06-21T12:47:57Z
dc.title.none.fl_str_mv Neuroimaging in attention-deficit/hyperactivity disorder
title Neuroimaging in attention-deficit/hyperactivity disorder
spellingShingle Neuroimaging in attention-deficit/hyperactivity disorder
Pereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949d
Attention-deficit/hyperactivity disorder
MRI
Neuroimaging
Personalized medicine
title_short Neuroimaging in attention-deficit/hyperactivity disorder
title_full Neuroimaging in attention-deficit/hyperactivity disorder
title_fullStr Neuroimaging in attention-deficit/hyperactivity disorder
title_full_unstemmed Neuroimaging in attention-deficit/hyperactivity disorder
title_sort Neuroimaging in attention-deficit/hyperactivity disorder
dc.creator.none.fl_str_mv Pereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949d
Castellanos, F.X. (Francisco X.)|||/items/96b377d4-821d-4950-bfb2-6d22cc924eba
author Pereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949d
author_facet Pereira-Sánchez, V. (Víctor)|||/items/af1d13b6-cb1b-43ec-a926-7387f05a949d
Castellanos, F.X. (Francisco X.)|||/items/96b377d4-821d-4950-bfb2-6d22cc924eba
author_role author
author2 Castellanos, F.X. (Francisco X.)|||/items/96b377d4-821d-4950-bfb2-6d22cc924eba
author2_role author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Attention-deficit/hyperactivity disorder
MRI
Neuroimaging
Personalized medicine
topic Attention-deficit/hyperactivity disorder
MRI
Neuroimaging
Personalized medicine
description Purpose of review: Neuroimaging research on attention-deficit/hyperactivity disorder (ADHD) continues growing in extent and complexity, although it has yet to become clinically meaningful. We review recent MRI research on ADHD, to identify robust findings, current trends and challenges. Recent findings: We identified 40 publications between January 2019 and September 2020 reporting or reviewing MRI research on ADHD. Four meta-analyses have presented conflicting results regarding across-study convergence of functional and resting-state functional (fMRI and R-fMRI) studies on ADHD. On the other hand, the Enhancing NeuroImaging Genetics Through Meta-Analysis international consortium has identified statistically robust albeit small differences in structural brain cortical and subcortical indices in children with ADHD versus typically developing controls. Other international consortia are harnessing open-science efforts and multimodal data (imaging, genetics, phenotypic) to shed light on the complex interplay of genetics, environment, and development in the pathophysiology of ADHD. We note growing research in 'prediction' science, which applies machine-learning analysis to identify biomarkers of disease based on big data. Summary: Neuroimaging in ADHD is still far from informing clinical practice. Current large-scale, multimodal, and open-science initiatives represent promising paths toward untangling the neurobiology of ADHD.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-01-01
2021
2021-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10171/116321
url https://hdl.handle.net/10171/116321
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wolters Kluwer Health, Inc.
publisher.none.fl_str_mv Wolters Kluwer Health, Inc.
dc.source.none.fl_str_mv reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra
instname:Universidad de Navarra
instname_str Universidad de Navarra
reponame_str Dadun. Depósito Académico Digital de la Universidad de Navarra
collection Dadun. Depósito Académico Digital de la Universidad de Navarra
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869412413936238592
score 15,81155

Similares en LA Referencia