Evaluation of Preclinical Efficacy of Curcumin-Loaded Bicosome Systems in Amelioration of Oral Mucositis

[Background/Objectives] Oral mucositis (OM) is a common and debilitating side effect of cancer therapy, characterized by ulceration or inflammation of the oral mucosa. This study evaluates the preclinical efficacy of curcumin-loaded bicosome systems (cur-BS) in mitigating chemotherapy-induced OM in...

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Detalles Bibliográficos
Autores: Vergara, Daniela, Sanhueza, Claudia, Méndez, Susana, Bustamante, Mariela, Vega, Benjamín, Acevedo, Francisca, López, Olga
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/382481
Acceso en línea:http://hdl.handle.net/10261/382481
Access Level:acceso abierto
Palabra clave:Curcumin
Bicosomes
Delivery systems
Ex vivo skin permeation
Oral mucositis
Descripción
Sumario:[Background/Objectives] Oral mucositis (OM) is a common and debilitating side effect of cancer therapy, characterized by ulceration or inflammation of the oral mucosa. This study evaluates the preclinical efficacy of curcumin-loaded bicosome systems (cur-BS) in mitigating chemotherapy-induced OM in mice.