Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative

Background: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College...

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Autores: Roest AM, de Vries YA, Pozuelo JR, Petukhova MV, Lee S, Sampson NA, Albor Y, Alhadi AN, Alonso J, Al-Saud N, Altwaijri Y, Andersson C, Atwoli L, Auerbach RP, Muaka CA, Báez-Mansur PM, Ballester L, Bantjes J, Baumeister H, Bendtsen M, Benjet C, Berman AH, Bruffaerts R, Carrasco P, Chan SCN, Cohut I, Couder MACD, Crockett MA, Cuijpers P, David OA, Dong D, Ebert DD, Gaete J, Forero CG, Gili M, Gutiérrez-García R, Haro JM, Hasking P, Hunt X, Husky MM, Jaguga F, Langer ÁI, Léniz I, Liu Y, Mac-Ginty S, Martínez V, McLafferty M, Miranda A, Monroy-Velasco IR, Murray EK, Musyoka CM, Nedelcea C, Núñez D, O'Neill SM, Piqueras JA, Popescu CA, Prescivalli AP, Rapsey C, Robinson K, Rodriguez-Jimenez T, Saal W, Siu OL, Stein DJ, Struijs SY, Tomoiaga CT, Valdés-García KP, Vargas-Contreras E, Vigo DV, Wang AY, Wong SYS, Kessler RC
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p28818
Acceso en línea:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28818
Access Level:acceso abierto
Palabra clave:Internalizing
Externalizing
Comorbidity
College students
Substance use disorders
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spelling Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiativeRoest AMde Vries YAPozuelo JRPetukhova MVLee SSampson NAAlbor YAlhadi ANAlonso JAl-Saud NAltwaijri YAndersson CAtwoli LAuerbach RPMuaka CABáez-Mansur PMBallester LBantjes JBaumeister HBendtsen MBenjet CBerman AHBruffaerts RCarrasco PChan SCNCohut ICouder MACDCrockett MACuijpers PDavid OADong DEbert DDGaete JForero CGGili MGutiérrez-García RHaro JMHasking PHunt XHusky MMJaguga FLanger ÁILéniz ILiu YMac-Ginty SMartínez VMcLafferty MMiranda AMonroy-Velasco IRMurray EKMusyoka CMNedelcea CNúñez DO'Neill SMPiqueras JAPopescu CAPrescivalli APRapsey CRobinson KRodriguez-Jimenez TSaal WSiu OLStein DJStruijs SYTomoiaga CTValdés-García KPVargas-Contreras EVigo DVWang AYWong SYSKessler RCInternalizingExternalizingComorbidityCollege studentsSubstance use disordersBackground: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023. Screening for common DSM-5 disorders was conducted using validated screening measures. Latent variables were examined using exploratory principal axis factor analysis on a correlation matrix among the lifetime mental disorders. Based on age-of-onset information, multivariable poisson regression models were used to examine associations of prior disorders with the first onset of other disorders. Results: 27.0 % of students screened positive for only one lifetime disorder, 17.1 % for two, 10.9 % for three, and 10.6 % for 4+ disorders. In the factor analysis, three latent variables were found, comprising: internalizing disorders (generalized anxiety disorder, major depressive episode, post-traumatic stress disorder, and panic disorder), substance use disorders (drug use disorder and alcohol use disorder), and externalizing disorders (attention deficit/hyperactivity disorder and mania/hypomania). Prior internalizing and externalizing disorders were associated with the subsequent first onset of all other disorders with risk ratios ranging from 1.5-7.5. Substance use disorders were less consistently associated with the subsequent first onset of other disorders, but alcohol use disorder was associated with the first onset of drug use disorder and vice versa. Conclusions: Mental disorder comorbidity is common among students, and students with disorders across the internalizing and externalizing spectrum have an increased risk of future mental disorder comorbidities.ELSEVIER IRELAND LTD2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28818PSYCHIATRY RESEARCHISSN: 01651781ISSNe: 18727123reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déuinstname:Fundació Sant Joan de DéuInglésinfo:eu-repo/semantics/openAccessoai:fsjd.fundanetsuite.com:p288182026-05-27T12:37:41Z
dc.title.none.fl_str_mv Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
title Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
spellingShingle Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
Roest AM
Internalizing
Externalizing
Comorbidity
College students
Substance use disorders
title_short Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
title_full Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
title_fullStr Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
title_full_unstemmed Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
title_sort Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative
dc.creator.none.fl_str_mv Roest AM
de Vries YA
Pozuelo JR
Petukhova MV
Lee S
Sampson NA
Albor Y
Alhadi AN
Alonso J
Al-Saud N
Altwaijri Y
Andersson C
Atwoli L
Auerbach RP
Muaka CA
Báez-Mansur PM
Ballester L
Bantjes J
Baumeister H
Bendtsen M
Benjet C
Berman AH
Bruffaerts R
Carrasco P
Chan SCN
Cohut I
Couder MACD
Crockett MA
Cuijpers P
David OA
Dong D
Ebert DD
Gaete J
Forero CG
Gili M
Gutiérrez-García R
Haro JM
Hasking P
Hunt X
Husky MM
Jaguga F
Langer ÁI
Léniz I
Liu Y
Mac-Ginty S
Martínez V
McLafferty M
Miranda A
Monroy-Velasco IR
Murray EK
Musyoka CM
Nedelcea C
Núñez D
O'Neill SM
Piqueras JA
Popescu CA
Prescivalli AP
Rapsey C
Robinson K
Rodriguez-Jimenez T
Saal W
Siu OL
Stein DJ
Struijs SY
Tomoiaga CT
Valdés-García KP
Vargas-Contreras E
Vigo DV
Wang AY
Wong SYS
Kessler RC
author Roest AM
author_facet Roest AM
de Vries YA
Pozuelo JR
Petukhova MV
Lee S
Sampson NA
Albor Y
Alhadi AN
Alonso J
Al-Saud N
Altwaijri Y
Andersson C
Atwoli L
Auerbach RP
Muaka CA
Báez-Mansur PM
Ballester L
Bantjes J
Baumeister H
Bendtsen M
Benjet C
Berman AH
Bruffaerts R
Carrasco P
Chan SCN
Cohut I
Couder MACD
Crockett MA
Cuijpers P
David OA
Dong D
Ebert DD
Gaete J
Forero CG
Gili M
Gutiérrez-García R
Haro JM
Hasking P
Hunt X
Husky MM
Jaguga F
Langer ÁI
Léniz I
Liu Y
Mac-Ginty S
Martínez V
McLafferty M
Miranda A
Monroy-Velasco IR
Murray EK
Musyoka CM
Nedelcea C
Núñez D
O'Neill SM
Piqueras JA
Popescu CA
Prescivalli AP
Rapsey C
Robinson K
Rodriguez-Jimenez T
Saal W
Siu OL
Stein DJ
Struijs SY
Tomoiaga CT
Valdés-García KP
Vargas-Contreras E
Vigo DV
Wang AY
Wong SYS
Kessler RC
author_role author
author2 de Vries YA
Pozuelo JR
Petukhova MV
Lee S
Sampson NA
Albor Y
Alhadi AN
Alonso J
Al-Saud N
Altwaijri Y
Andersson C
Atwoli L
Auerbach RP
Muaka CA
Báez-Mansur PM
Ballester L
Bantjes J
Baumeister H
Bendtsen M
Benjet C
Berman AH
Bruffaerts R
Carrasco P
Chan SCN
Cohut I
Couder MACD
Crockett MA
Cuijpers P
David OA
Dong D
Ebert DD
Gaete J
Forero CG
Gili M
Gutiérrez-García R
Haro JM
Hasking P
Hunt X
Husky MM
Jaguga F
Langer ÁI
Léniz I
Liu Y
Mac-Ginty S
Martínez V
McLafferty M
Miranda A
Monroy-Velasco IR
Murray EK
Musyoka CM
Nedelcea C
Núñez D
O'Neill SM
Piqueras JA
Popescu CA
Prescivalli AP
Rapsey C
Robinson K
Rodriguez-Jimenez T
Saal W
Siu OL
Stein DJ
Struijs SY
Tomoiaga CT
Valdés-García KP
Vargas-Contreras E
Vigo DV
Wang AY
Wong SYS
Kessler RC
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
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author
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dc.subject.none.fl_str_mv Internalizing
Externalizing
Comorbidity
College students
Substance use disorders
topic Internalizing
Externalizing
Comorbidity
College students
Substance use disorders
description Background: Mental disorders are highly prevalent among students worldwide. This study aims to examine comorbidity and temporal associations between mental disorders among students. Methods: The study included 72,288 students from 18 countries as part of the World Mental Health International College Student (WMH-ICS) Initiative, with cross-sectional data collected between 2017 and 2023. Screening for common DSM-5 disorders was conducted using validated screening measures. Latent variables were examined using exploratory principal axis factor analysis on a correlation matrix among the lifetime mental disorders. Based on age-of-onset information, multivariable poisson regression models were used to examine associations of prior disorders with the first onset of other disorders. Results: 27.0 % of students screened positive for only one lifetime disorder, 17.1 % for two, 10.9 % for three, and 10.6 % for 4+ disorders. In the factor analysis, three latent variables were found, comprising: internalizing disorders (generalized anxiety disorder, major depressive episode, post-traumatic stress disorder, and panic disorder), substance use disorders (drug use disorder and alcohol use disorder), and externalizing disorders (attention deficit/hyperactivity disorder and mania/hypomania). Prior internalizing and externalizing disorders were associated with the subsequent first onset of all other disorders with risk ratios ranging from 1.5-7.5. Substance use disorders were less consistently associated with the subsequent first onset of other disorders, but alcohol use disorder was associated with the first onset of drug use disorder and vice versa. Conclusions: Mental disorder comorbidity is common among students, and students with disorders across the internalizing and externalizing spectrum have an increased risk of future mental disorder comorbidities.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28818
url https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=28818
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv ELSEVIER IRELAND LTD
publisher.none.fl_str_mv ELSEVIER IRELAND LTD
dc.source.none.fl_str_mv PSYCHIATRY RESEARCH
ISSN: 01651781
ISSNe: 18727123
reponame:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname:Fundació Sant Joan de Déu
instname_str Fundació Sant Joan de Déu
reponame_str r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
collection r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
repository.name.fl_str_mv
repository.mail.fl_str_mv
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