Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations

Objectives: To investigate the extent to which articles of economic evaluations of healthcare interventions indexed in MEDLINE incorporate research practices that promote transparency, openness, and reproducibility. Study design and setting: We evaluated a random sample of health economic evaluation...

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Autores: Catalá-López, Ferrán, Ridao, Manuel, Tejedor Romero, Laura, Caulley, Lisa, Hutton, Brian, Husereau, Don, Alonso-Arroyo, Adolfo, Bernal-Delgado, Enrique, Drummond, Michael F, Moher, David
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/17385
Acceso en línea:http://hdl.handle.net/20.500.12105/17385
Access Level:acceso abierto
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spelling Transparency, openness, and reproducible research practices are frequently underused in health economic evaluationsCatalá-López, FerránRidao, ManuelTejedor Romero, LauraCaulley, LisaHutton, BrianHusereau, DonAlonso-Arroyo, AdolfoBernal-Delgado, EnriqueDrummond, Michael FMoher, DavidObjectives: To investigate the extent to which articles of economic evaluations of healthcare interventions indexed in MEDLINE incorporate research practices that promote transparency, openness, and reproducibility. Study design and setting: We evaluated a random sample of health economic evaluations indexed in MEDLINE during 2019. We included articles written in English reporting an incremental cost-effectiveness ratio in terms of costs per life years gained, quality-adjusted life years, and/or disability-adjusted life years. Reproducible research practices, openness, and transparency in each article were extracted in duplicate. We explored whether reproducible research practices were associated with self-report use of a guideline. Results: We included 200 studies published in 147 journals. Almost half were published as open access articles (n = 93; 47%). Most studies (n = 150; 75%) were model-based economic evaluations. In 109 (55%) studies, authors self-reported use a guideline (e.g., for study conduct or reporting). Few studies (n = 31; 16%) reported working from a protocol. In 112 (56%) studies, authors reported the data needed to recreate the incremental cost-effectiveness ratio for the base case analysis. This percentage was higher in studies using a guideline than studies not using a guideline (72/109 [66%] with guideline vs. 40/91 [44%] without guideline; risk ratio 1.50, 95% confidence interval 1.15-1.97). Only 10 (5%) studies mentioned access to raw data and analytic code for reanalyses. Conclusion: Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations. This study provides baseline data to compare future progress in the field.WileyInstituto de Salud Carlos IIICentro de Investigación Biomédica en Red - CIBERSAM (Salud Mental)University of Ottawa (Canadá)20242024-01-3120242024-01-0120242024-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/20.500.12105/17385reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/173852026-06-12T12:43:37Z
dc.title.none.fl_str_mv Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
title Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
spellingShingle Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
Catalá-López, Ferrán
title_short Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
title_full Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
title_fullStr Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
title_full_unstemmed Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
title_sort Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations
dc.creator.none.fl_str_mv Catalá-López, Ferrán
Ridao, Manuel
Tejedor Romero, Laura
Caulley, Lisa
Hutton, Brian
Husereau, Don
Alonso-Arroyo, Adolfo
Bernal-Delgado, Enrique
Drummond, Michael F
Moher, David
author Catalá-López, Ferrán
author_facet Catalá-López, Ferrán
Ridao, Manuel
Tejedor Romero, Laura
Caulley, Lisa
Hutton, Brian
Husereau, Don
Alonso-Arroyo, Adolfo
Bernal-Delgado, Enrique
Drummond, Michael F
Moher, David
author_role author
author2 Ridao, Manuel
Tejedor Romero, Laura
Caulley, Lisa
Hutton, Brian
Husereau, Don
Alonso-Arroyo, Adolfo
Bernal-Delgado, Enrique
Drummond, Michael F
Moher, David
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Salud Carlos III
Centro de Investigación Biomédica en Red - CIBERSAM (Salud Mental)
University of Ottawa (Canadá)
description Objectives: To investigate the extent to which articles of economic evaluations of healthcare interventions indexed in MEDLINE incorporate research practices that promote transparency, openness, and reproducibility. Study design and setting: We evaluated a random sample of health economic evaluations indexed in MEDLINE during 2019. We included articles written in English reporting an incremental cost-effectiveness ratio in terms of costs per life years gained, quality-adjusted life years, and/or disability-adjusted life years. Reproducible research practices, openness, and transparency in each article were extracted in duplicate. We explored whether reproducible research practices were associated with self-report use of a guideline. Results: We included 200 studies published in 147 journals. Almost half were published as open access articles (n = 93; 47%). Most studies (n = 150; 75%) were model-based economic evaluations. In 109 (55%) studies, authors self-reported use a guideline (e.g., for study conduct or reporting). Few studies (n = 31; 16%) reported working from a protocol. In 112 (56%) studies, authors reported the data needed to recreate the incremental cost-effectiveness ratio for the base case analysis. This percentage was higher in studies using a guideline than studies not using a guideline (72/109 [66%] with guideline vs. 40/91 [44%] without guideline; risk ratio 1.50, 95% confidence interval 1.15-1.97). Only 10 (5%) studies mentioned access to raw data and analytic code for reanalyses. Conclusion: Transparency, openness, and reproducible research practices are frequently underused in health economic evaluations. This study provides baseline data to compare future progress in the field.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-01-31
2024
2024-01-01
2024
2024-01-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/17385
url http://hdl.handle.net/20.500.12105/17385
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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