The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review

Acute respiratory distress syndrome (ARDS) is defined as the acute onset of noncardiogenic edema and subsequent gas-exchange impairment due to a severe inflammatory process. Recent report on the prognostic value of eicosanoids in patients with ARDS suggests that modulating the inflammatory response...

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Autores: García de Acilu, M., Leal, S., Caralt, B., Roca, O., Sabater Riera, Joan, Masclans, Joan R.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/126166
Acceso en línea:https://hdl.handle.net/2445/126166
Access Level:acceso abierto
Palabra clave:Malalties de l'aparell respiratori
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spelling The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical ReviewGarcía de Acilu, M.Leal, S.Caralt, B.Roca, O.Sabater Riera, JoanMasclans, Joan R.Malalties de l'aparell respiratoriMalalties de l'aparell respiratoriAcute respiratory distress syndrome (ARDS) is defined as the acute onset of noncardiogenic edema and subsequent gas-exchange impairment due to a severe inflammatory process. Recent report on the prognostic value of eicosanoids in patients with ARDS suggests that modulating the inflammatory response through the use of polyunsaturated fatty acids may be a useful strategy for ARDS treatment. The use of enteral diets enriched with eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) has reported promising results, showing an improvement in respiratory variables and haemodynamics. However, the interpretation of the studies is limited by their heterogeneity and methodology and the effect of omega-3 fatty acid-enriched lipid emulsion or enteral diets on patients with ARDS remains unclear. Therefore, the routine use of omega-3 fatty acid-enriched nutrition cannot be recommended and further large, homogeneous, and high-quality clinical trials need to be conducted to clarify the effectiveness of omega-3 polyunsaturated fatty acids.Hindawi Publishing Corporation2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/126166Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1155/2015/653750BioMed Research International, 2015, vol. 2015https://doi.org/10.1155/2015/653750cc by (c) García de Acilu et al., 2015http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1261662026-05-27T06:46:51Z
dc.title.none.fl_str_mv The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
title The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
spellingShingle The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
García de Acilu, M.
Malalties de l'aparell respiratori
Malalties de l'aparell respiratori
title_short The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
title_full The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
title_fullStr The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
title_full_unstemmed The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
title_sort The Role Of Omega-3 Polyunsaturated Fatty Acids In The Treatment Of Patients With Acute Respiratory Distress Syndrome: A Clinical Review
dc.creator.none.fl_str_mv García de Acilu, M.
Leal, S.
Caralt, B.
Roca, O.
Sabater Riera, Joan
Masclans, Joan R.
author García de Acilu, M.
author_facet García de Acilu, M.
Leal, S.
Caralt, B.
Roca, O.
Sabater Riera, Joan
Masclans, Joan R.
author_role author
author2 Leal, S.
Caralt, B.
Roca, O.
Sabater Riera, Joan
Masclans, Joan R.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Malalties de l'aparell respiratori
Malalties de l'aparell respiratori
topic Malalties de l'aparell respiratori
Malalties de l'aparell respiratori
description Acute respiratory distress syndrome (ARDS) is defined as the acute onset of noncardiogenic edema and subsequent gas-exchange impairment due to a severe inflammatory process. Recent report on the prognostic value of eicosanoids in patients with ARDS suggests that modulating the inflammatory response through the use of polyunsaturated fatty acids may be a useful strategy for ARDS treatment. The use of enteral diets enriched with eicosapentaenoic acid (EPA) and gamma-linolenic acid (GLA) has reported promising results, showing an improvement in respiratory variables and haemodynamics. However, the interpretation of the studies is limited by their heterogeneity and methodology and the effect of omega-3 fatty acid-enriched lipid emulsion or enteral diets on patients with ARDS remains unclear. Therefore, the routine use of omega-3 fatty acid-enriched nutrition cannot be recommended and further large, homogeneous, and high-quality clinical trials need to be conducted to clarify the effectiveness of omega-3 polyunsaturated fatty acids.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/126166
url https://hdl.handle.net/2445/126166
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1155/2015/653750
BioMed Research International, 2015, vol. 2015
https://doi.org/10.1155/2015/653750
dc.rights.none.fl_str_mv cc by (c) García de Acilu et al., 2015
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) García de Acilu et al., 2015
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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