Factors influencing xerostomia and oral health‐related quality of life in polymedicated patients

Objectives To evaluate whether the severity of xerostomia in older polymedicated patients impacts oral health-related quality of life (OHRQoL). Background Medication-associated xerostomia is common in older people. Xerostomia may impair OHRQoL. Materials and methods This cross-sectional study includ...

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Detalles Bibliográficos
Autores: Ramírez Martínez-Acitores, Lucía, Sánchez Garrido, Isabel, González Serrano, José, Muñoz, Marta, Martínez-Acitores, María Luisa, Garrido, Estela, Hernández Vallejo, Gonzalo, López-Pintor Muñoz, Rosa María
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/92667
Acceso en línea:https://hdl.handle.net/20.500.14352/92667
Access Level:acceso abierto
Palabra clave:616.314-053.9
Hyposalivation
Medications
Oral health impact profile
Quality of life
Salivary flow
Xerostomia
Xerostomia inventory
Odontología (Odontología)
Geriatría
Medicamentos
32 Ciencias Médicas
3213.13 Ortodoncia-Estomatología
3201.07 Geriatría
Descripción
Sumario:Objectives To evaluate whether the severity of xerostomia in older polymedicated patients impacts oral health-related quality of life (OHRQoL). Background Medication-associated xerostomia is common in older people. Xerostomia may impair OHRQoL. Materials and methods This cross-sectional study included older hypertensive patients from two health centres. We assessed the severity of xerostomia and OHRQoL using the Xerostomia Inventory (XI) tool, and the Oral Health Impact Profile-14 (OHIP-14) instrument, respectively. We measured unstimulated (UWS) and stimulated (SWS) salivary flows. Univariate and multiple linear regression analyses evaluated the associations of XI and OHIP-14 and different explanatory variables. Results Of the 218 patients enrolled, 51.8% had xerostomia, and 38.1% and 27.5% suffered from UWS and SWS hyposalivation, respectively. Patients with xerostomia, UWS, and SWS hyposalivation scored significantly higher on the XI. However, only those with xerostomia or UWS hyposalivation had significantly higher OHIP-14 scores. A moderate correlation was observed between XI and OHIP-14 scores. The multiple regression model showed that factors with the greatest impact on XI were the patient's complaint of xerostomia, UWS flow rate, age and sex. However, only the XI score was significantly associated with the OHIP-14 score. Conclusion Xerostomia has a negative impact on OHRQoL in older polymedicated patients, but this impact is less than in other types of xerostomia. Longitudinal studies are needed to determine whether changes in the detected explanatory variables influence XI and OHIP scores in these patients.