Surface functionalization of graphene oxide with tannic acid: Covalent vs non-covalent approaches

Graphene oxide (GO) is gaining a lot of interest in material science, biomedicine and biotechnology due to its outstanding physical properties, combined with its surface functionalization capacity, processability in aqueous media and biocompatibility. However, van der Waals forces among GO layers re...

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Detalles Bibliográficos
Autores: Sainz-Urruela, Carlos, Vera-López, Soledad, San Andrés, María Paz, Diez-Pascual, Ana María
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consorcio Madroño
Repositorio:e-cienciaDatos, Repositorio de Datos del Consorcio Madroño
OAI Identifier:doi:10.21950/1HRTJH
Acceso en línea:https://doi.org/10.21950/1HRTJH
Access Level:acceso abierto
Palabra clave:Chemistry
Surface functionalization
Tannic acid
Graphene oxide
Bioactive compound
Covalent grafting
Descripción
Sumario:Graphene oxide (GO) is gaining a lot of interest in material science, biomedicine and biotechnology due to its outstanding physical properties, combined with its surface functionalization capacity, processability in aqueous media and biocompatibility. However, van der Waals forces among GO layers result in aggregation, yet its dispersion, large-scale production, and reinforcing efficiency remain challenging. In this project, simple and environmentally friendly methods via covalent and non-covalent routes have been developed to exfoliate and prepare surface-functionalized GO nanosheets with tannic acid (TA), a biological macromolecule with antioxidant activity. Four esterification strategies were tested: direct, carbodiimide activated, oxalyl chloride acylation and via an acid-functionalized GO intermediate. The resulting samples have been extensively characterized to get knowledge on the GO-TA interactions and the degree of grafting, as well as their surface topography, level of hydrophilicity, solubility/dispersibility, thermal and antibacterial properties. The covalent grafting of TA renders the GO surface more hydrophobic, resulting in improved dispersion in organic solvents. Besides, TA acts as a crosslinker between the GO nanosheets, leading to higher thermal resistance. A synergistic effect of both GO and TA on inhibiting bacterial growth has also been found. The esterification via carbodiimide leads to the highest grafting degree, the best thermal stability and the most effective antibacterial activity. This work not only highlights the great potential of TA for both exfoliation and surface functionalization of GO, but also extends its applications in biomedicine and for the development of green nanocomposites.