Azonia derivatives of the γ-carboline system. A new class of DNA intercalators
1-Methyl-γ-carboline derivatives were transformed into the corresponding N-aminoazinium salts, which were condensed with 1,2-dicarbonyl compounds (Westphal reaction) to afford azonia derivatives with a bridgehead quaternary nitrogen atom. Some of them show DNA intercalating properties.
| Autores: | , , , , , , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 1996 |
| País: | España |
| Institución: | Universidad de Alcalá (UAH) |
| Repositorio: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglés |
| OAI Identifier: | oai:ebuah.uah.es:10017/4176 |
| Acceso en línea: | http://hdl.handle.net/10017/4176 https://dx.doi.org/10.1016/S0960-894X(96)00243-0 |
| Access Level: | acceso abierto |
| Palabra clave: | DNA intercalators γ-carboline system Azonia derivatives Ciencia Química orgánica Science Chemistry, organic |
| Sumario: | 1-Methyl-γ-carboline derivatives were transformed into the corresponding N-aminoazinium salts, which were condensed with 1,2-dicarbonyl compounds (Westphal reaction) to afford azonia derivatives with a bridgehead quaternary nitrogen atom. Some of them show DNA intercalating properties. |
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