Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro

[eng] Introduction: Urine sediment testing is a diagnostic medicine that remains a long-standing practice in clinical laboratories. Urine analysis, which is an important test in clinical medicine, is used in screening, diagnosing and monitoring diseases of the urinary system, and d...

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Autores: Ilkovska Biljana, Kotevska Trifunova, Bisera, Avramovski, Petar
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Recursos:Universidad de las Islas Baleares
Repositorio:Biblioteca Digital de les Illes Balears
OAI Identifier:medicinaBalear:AJHS_Medicina_Balear_2025v40n2p027
Acesso em linha:http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/5v40n2p0/27.dir/AJHS_Medicina_Balear_2025v40n2p027.pdf
http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2025v40n2p027
Access Level:acceso abierto
Palavra-chave:Urine--Analysis
Health Sciences
Medicine
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network_name_str España
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dc.title.none.fl_str_mv Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
title Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
spellingShingle Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
Ilkovska Biljana
Urine--Analysis
Health Sciences
Medicine
title_short Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
title_full Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
title_fullStr Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
title_full_unstemmed Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
title_sort Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 Pro
dc.creator.none.fl_str_mv Ilkovska Biljana
Kotevska Trifunova, Bisera
Avramovski, Petar
author Ilkovska Biljana
author_facet Ilkovska Biljana
Kotevska Trifunova, Bisera
Avramovski, Petar
author_role author
author2 Kotevska Trifunova, Bisera
Avramovski, Petar
author2_role author
author
dc.subject.none.fl_str_mv Urine--Analysis
Health Sciences
Medicine
topic Urine--Analysis
Health Sciences
Medicine
description [eng] Introduction: Urine sediment testing is a diagnostic medicine that remains a long-standing practice in clinical laboratories. Urine analysis, which is an important test in clinical medicine, is used in screening, diagnosing and monitoring diseases of the urinary system, and diseases that are detected through the urinary system. We use the performance of a new model of UriSed (also sediMAX) automated microscope called UriSed 3 PRO. Thus, this paper presents a case of interest for clinical laboratory practice, as it demonstrates the utility of urine sediment examination as a diagnostic tool in the evaluation kidney disease. Therefore, we summarized the data from 3200 urinalysis and our aim was to evaluate the distribution of urinary crystal components and different crystal forms according to the age and gender of the patients. Methods: The study was performed using 3200 urine samples collected into the clean tubes without preservatives, which have been obtained from the patients applied to Hospital for routine visit. The patients left the urine samples and we pipette 10 mL into test tubes. The samples were analyzed every day in small batches for six months in 2023.The urine sample were analyzed in an hour at the latest. Results: Of the 3200 urines analyzed, 2000 females and 1200 males. 2079 of them were free of crystals and 1121 urines were with crystals and were included in the analysis. 67% were mostly calcium oxalate dihydrate crystals, followed by calcium oxalate monohydrate 22%, followed by 11% triple phosphate crystals and 0.01% uric acid crystals. The majority of crystals were detected in males (37%) versus females (33%). Calcium oxalate dihydrate crystals (26% vs.22%) was the most common major component in both men and women, followed by crystals of calcium oxalate monohydrate (8% vs.7%). Conclusion: The most abundant crystals in the urine in our study were found to be calcium oxalate crystals, followed by tripel phosphate and uric acid. The highest incidence of crystals is in patients aged 61 to 70 years. The male gender is more affected compared to the female gender. The distinction between different crystal forms can provide clues to the activity and mechanisms of the lithogenic process. Knowledge of the mechanisms of crystal and stone formation is necessary in order to provide appropriate individualized treatment to each patient and to prevent their recurrence.
publishDate 2025
dc.date.none.fl_str_mv 2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/5v40n2p0/27.dir/AJHS_Medicina_Balear_2025v40n2p027.pdf
http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2025v40n2p027
url http://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/5v40n2p0/27.dir/AJHS_Medicina_Balear_2025v40n2p027.pdf
http://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2025v40n2p027
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Academic Journal of Health Sciences 2025, vol. 40, n. 2, pp. 27-31
dc.rights.none.fl_str_mv All rights reserved
info:eu-repo/semantics/openAccess
rights_invalid_str_mv All rights reserved
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Reial Acadèmia de Medicina de les Illes Balears
publisher.none.fl_str_mv Reial Acadèmia de Medicina de les Illes Balears
dc.source.none.fl_str_mv reponame:Biblioteca Digital de les Illes Balears
instname:Universidad de las Islas Baleares
instname_str Universidad de las Islas Baleares
reponame_str Biblioteca Digital de les Illes Balears
collection Biblioteca Digital de les Illes Balears
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling Urine sediment crystals in Bitola, North Macedonia: results from 3200 urines made with LabUMat 2 & Urised 3 ProIlkovska BiljanaKotevska Trifunova, BiseraAvramovski, PetarUrine--AnalysisHealth SciencesMedicine[eng] Introduction: Urine sediment testing is a diagnostic medicine that remains a long-standing practice in clinical laboratories. Urine analysis, which is an important test in clinical medicine, is used in screening, diagnosing and monitoring diseases of the urinary system, and diseases that are detected through the urinary system. We use the performance of a new model of UriSed (also sediMAX) automated microscope called UriSed 3 PRO. Thus, this paper presents a case of interest for clinical laboratory practice, as it demonstrates the utility of urine sediment examination as a diagnostic tool in the evaluation kidney disease. Therefore, we summarized the data from 3200 urinalysis and our aim was to evaluate the distribution of urinary crystal components and different crystal forms according to the age and gender of the patients. Methods: The study was performed using 3200 urine samples collected into the clean tubes without preservatives, which have been obtained from the patients applied to Hospital for routine visit. The patients left the urine samples and we pipette 10 mL into test tubes. The samples were analyzed every day in small batches for six months in 2023.The urine sample were analyzed in an hour at the latest. Results: Of the 3200 urines analyzed, 2000 females and 1200 males. 2079 of them were free of crystals and 1121 urines were with crystals and were included in the analysis. 67% were mostly calcium oxalate dihydrate crystals, followed by calcium oxalate monohydrate 22%, followed by 11% triple phosphate crystals and 0.01% uric acid crystals. The majority of crystals were detected in males (37%) versus females (33%). Calcium oxalate dihydrate crystals (26% vs.22%) was the most common major component in both men and women, followed by crystals of calcium oxalate monohydrate (8% vs.7%). Conclusion: The most abundant crystals in the urine in our study were found to be calcium oxalate crystals, followed by tripel phosphate and uric acid. The highest incidence of crystals is in patients aged 61 to 70 years. The male gender is more affected compared to the female gender. The distinction between different crystal forms can provide clues to the activity and mechanisms of the lithogenic process. Knowledge of the mechanisms of crystal and stone formation is necessary in order to provide appropriate individualized treatment to each patient and to prevent their recurrence.[spa] Introducción: El análisis del sedimento urinario es una prueba diagnóstica que sigue siendo una práctica arraigada en los laboratorios clínicos. El análisis de orina, que es una prueba importante en la medicina clínica, se utiliza en el cribado, diagnóstico y seguimiento de enfermedades del aparato urinario y de enfermedades que se detectan a través del aparato urinario. Utilizamos el rendimiento de un nuevo modelo de microscopio automatizado UriSed (también sediMAX) denominado UriSed 3 PRO. Así, este trabajo presenta un caso de interés para la práctica del laboratorio clínico, ya que demuestra la utilidad del examen del sedimento urinario como herramienta diagnóstica en la evaluación de la enfermedad renal. Por lo tanto, resumimos los datos de 3200 análisis de orina y nuestro objetivo fue evaluar la distribución de los componentes de los cristales urinarios y las diferentes formas de cristales según la edad y el sexo de los pacientes. Métodos: El estudio se realizó utilizando 3200 muestras de orina recogidas en tubos limpios sin conservantes, obtenidas de pacientes que acudieron al hospital para una visita rutinaria. Los pacientes dejaron las muestras de orina y pipeteamos 10 mL en tubos de ensayo. Las muestras se analizaron todos los días en pequeños lotes durante seis meses en 2023.La muestra de orina se analizaron en una hora a más tardar. Resultados: De las 3200 orinas analizadas, 2000 eran de mujeres y 1200 de hombres. 2079 de ellas estaban libres de cristales y 1121 orinas estaban con cristales y se incluyeron en el análisis. El 67% eran en su mayoría cristales de oxalato cálcico dihidratado, seguido de oxalato cálcico monohidratado 22%, seguido de un 11% de cristales de fosfato triple y un 0,01% de cristales de ácido úrico. La mayoría de los cristales se detectaron en varones (37%) frente a mujeres (33%). Los cristales de oxalato cálcico dihidratado (26% frente a 22%) fueron el componente principal más frecuente tanto en hombres como en mujeres, seguidos de los cristales de oxalato cálcico monohidratado (8% frente a 7%). Conclusión: Los cristales más abundantes en la orina de nuestro estudio fueron los de oxalato cálcico, seguidos de los de tripel fosfato y ácido úrico. La mayor incidencia de cristales se da en pacientes de 61 a 70 años. El sexo masculino está más afectado que el femenino. La distinción entre las diferentes formas cristalinas puede proporcionar pistas sobre la actividad y los mecanismos del proceso litogénico. El conocimiento de los mecanismos de formación de cristales y cálculos es necesario para proporcionar un tratamiento individualizado adecuado a cada paciente y prevenir su recurrencia.Reial Acadèmia de Medicina de les Illes Balears2025info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://ibdigital.uib.es/greenstone/sites/oai-site/collect/medicinaBalear/index/assoc/AJHS_Med/icina_Ba/lear_202/5v40n2p0/27.dir/AJHS_Medicina_Balear_2025v40n2p027.pdfhttp://ibdigital.uib.es/greenstone/library/collection/medicinaBalear/document/AJHS_Medicina_Balear_2025v40n2p027reponame:Biblioteca Digital de les Illes Balearsinstname:Universidad de las Islas BalearesInglésAcademic Journal of Health Sciences 2025, vol. 40, n. 2, pp. 27-31All rights reservedinfo:eu-repo/semantics/openAccessmedicinaBalear:AJHS_Medicina_Balear_2025v40n2p0272026-05-28T12:40:11Z
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