Safe use of proton-pump inhibitors
Proton-pump inhibitors (PPIs) are one of the most widely used drug classes worldwide. Their discovery goes back to the 1980s, when the significance of H+/K+-ATPase in gastric acid production was established. The market launch of PPIs, which inhibit this enzyme by direct, irreversible binding, paved...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Universidad de Sevilla (US) |
| Repositorio: | idUS. Depósito de Investigación de la Universidad de Sevilla |
| OAI Identifier: | oai:idus.us.es:11441/157215 |
| Acceso en línea: | https://hdl.handle.net/11441/157215 https://doi.org/10.17235/reed.2023.9834/2023 |
| Access Level: | acceso abierto |
| Palabra clave: | Proton-pump inhibitors Gastrointestinal Drugs |
| Sumario: | Proton-pump inhibitors (PPIs) are one of the most widely used drug classes worldwide. Their discovery goes back to the 1980s, when the significance of H+/K+-ATPase in gastric acid production was established. The market launch of PPIs, which inhibit this enzyme by direct, irreversible binding, paved the way to a new age in the management of gastrointestinal conditions related to stomach acid secretion (1). |
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