Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis

Objective. To examine the grade of agreement between very low disease activity (VLDA) and Disease Activity Index for Psoriatic Arthritis (DAPSA) remission, as well as their association with the effect of the disease as assessed by the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire in pa...

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Autores: Queiro, Rubén, Cañete, Juan D., Montilla, Carlos, Abad, Miguel Ángel, Montoro, María, Gómez, Susana, Cábez, Ana, Román Ivorra, José Andrés
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/5130
Acceso en línea:http://hdl.handle.net/20.500.12466/5130
Access Level:acceso abierto
Palabra clave:Disease Activity
Remission
Psoriatic Arthritis
Disease Activity Criteria
3205.09 Reumatología
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spelling Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic ArthritisQueiro, RubénCañete, Juan D.Montilla, CarlosAbad, Miguel ÁngelMontoro, MaríaGómez, SusanaCábez, AnaRomán Ivorra, José AndrésDisease ActivityRemissionPsoriatic ArthritisDisease Activity Criteria3205.09 ReumatologíaObjective. To examine the grade of agreement between very low disease activity (VLDA) and Disease Activity Index for Psoriatic Arthritis (DAPSA) remission, as well as their association with the effect of the disease as assessed by the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire in patients with psoriatic arthritis in routine clinical practice. Methods. Posthoc analysis of data from a cross-sectional multicenter study. Patients were included who fulfilled the Classification for Psoriatic Arthritis (CASPAR) criteria with at least 1 year of disease duration and were treated with biological and/or conventional synthetic disease-modifying antirheumatic drugs according to routine clinical practice in Spain. Patients were considered in VLDA if they met 7/7 of the minimal disease activity criteria. DAPSA and clinical (c)DAPSA score ≤ 4 identified remissions. Results. Of the 227 patients included in the original study, 26 (11.5%), 52 (22.9%), and 65 (28.6%) were in VLDA, DAPSA remission, and cDAPSA remission, respectively. There was a moderate agreement between VLDA and DAPSA remission (k = 0.52) or cDAPSA remission (k = 0.42). Patients with VLDA had less effect of the disease as measured by PsAID [mean total score (SD): VLDA 1.1 (1.2); DAPSA remission 1.3 (1.5); cDAPSA remission 1.7 (1.6)]. There was a moderate agreement between DAPSA remission or cDAPSA remission and PsAID < 4 (k = 0.46 and k = 0.58 respectively), while poor agreement (k = 0.18) was found between VLDA and PsAID < 4. Conclusion. VLDA criteria seem to be more stringent for assessing a status of remission; however, DAPSA remission shows better correlation with a patient-acceptable symptoms state than VLDA does. (First Release February 1 2019; J Rheumatol 2019;46:710–15; doi:10.3899/jrheum.180460)20252025-01-1420192019-07-0120192019-07-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/20.500.12466/5130reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártirinstname:Universidad Católica de Valencia San Vicente MártirInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:riucv.ucv.es:20.500.12466/51302026-06-19T08:32:07Z
dc.title.none.fl_str_mv Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
title Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
spellingShingle Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
Queiro, Rubén
Disease Activity
Remission
Psoriatic Arthritis
Disease Activity Criteria
3205.09 Reumatología
title_short Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
title_full Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
title_fullStr Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
title_full_unstemmed Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
title_sort Very Low Disease Activity, DAPSA Remission, and Impact of Disease in a Spanish Population with Psoriatic Arthritis
dc.creator.none.fl_str_mv Queiro, Rubén
Cañete, Juan D.
Montilla, Carlos
Abad, Miguel Ángel
Montoro, María
Gómez, Susana
Cábez, Ana
Román Ivorra, José Andrés
author Queiro, Rubén
author_facet Queiro, Rubén
Cañete, Juan D.
Montilla, Carlos
Abad, Miguel Ángel
Montoro, María
Gómez, Susana
Cábez, Ana
Román Ivorra, José Andrés
author_role author
author2 Cañete, Juan D.
Montilla, Carlos
Abad, Miguel Ángel
Montoro, María
Gómez, Susana
Cábez, Ana
Román Ivorra, José Andrés
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Disease Activity
Remission
Psoriatic Arthritis
Disease Activity Criteria
3205.09 Reumatología
topic Disease Activity
Remission
Psoriatic Arthritis
Disease Activity Criteria
3205.09 Reumatología
description Objective. To examine the grade of agreement between very low disease activity (VLDA) and Disease Activity Index for Psoriatic Arthritis (DAPSA) remission, as well as their association with the effect of the disease as assessed by the Psoriatic Arthritis Impact of Disease (PsAID) questionnaire in patients with psoriatic arthritis in routine clinical practice. Methods. Posthoc analysis of data from a cross-sectional multicenter study. Patients were included who fulfilled the Classification for Psoriatic Arthritis (CASPAR) criteria with at least 1 year of disease duration and were treated with biological and/or conventional synthetic disease-modifying antirheumatic drugs according to routine clinical practice in Spain. Patients were considered in VLDA if they met 7/7 of the minimal disease activity criteria. DAPSA and clinical (c)DAPSA score ≤ 4 identified remissions. Results. Of the 227 patients included in the original study, 26 (11.5%), 52 (22.9%), and 65 (28.6%) were in VLDA, DAPSA remission, and cDAPSA remission, respectively. There was a moderate agreement between VLDA and DAPSA remission (k = 0.52) or cDAPSA remission (k = 0.42). Patients with VLDA had less effect of the disease as measured by PsAID [mean total score (SD): VLDA 1.1 (1.2); DAPSA remission 1.3 (1.5); cDAPSA remission 1.7 (1.6)]. There was a moderate agreement between DAPSA remission or cDAPSA remission and PsAID < 4 (k = 0.46 and k = 0.58 respectively), while poor agreement (k = 0.18) was found between VLDA and PsAID < 4. Conclusion. VLDA criteria seem to be more stringent for assessing a status of remission; however, DAPSA remission shows better correlation with a patient-acceptable symptoms state than VLDA does. (First Release February 1 2019; J Rheumatol 2019;46:710–15; doi:10.3899/jrheum.180460)
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-07-01
2019
2019-07-01
2025
2025-01-14
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12466/5130
url http://hdl.handle.net/20.500.12466/5130
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.source.none.fl_str_mv reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
instname:Universidad Católica de Valencia San Vicente Mártir
instname_str Universidad Católica de Valencia San Vicente Mártir
reponame_str RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
collection RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
repository.name.fl_str_mv
repository.mail.fl_str_mv
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