Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications

The project is aimed at investigating the effect of laser surface modification of dental-grade zirconia (3Y-TZP) to guide cellular behaviour. A nanosecond laser was employed to fabricate groove patterns on the surface of 3Y-TZP, yielding three different topographies according to the groove periodici...

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Autores: García de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139, Roa Rovira, Joan Josep|||0000-0002-7440-0766, Mas Moruno, Carlos|||0000-0001-8337-0872
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/369461
Acesso em linha:https://hdl.handle.net/2117/369461
Access Level:acceso abierto
Palavra-chave:Zirconium
Lasers
Zirconia
Laser patterning
Topography
Phase transformation
Hydrothermal degradation
Cell adhesion
Zirconi
Làsers
Àrees temàtiques de la UPC::Enginyeria dels materials
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repository_id_str
spelling Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applicationsGarcía de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139Roa Rovira, Joan Josep|||0000-0002-7440-0766Mas Moruno, Carlos|||0000-0001-8337-0872ZirconiumLasersZirconiaLaser patterningTopographyPhase transformationHydrothermal degradationCell adhesionZirconiLàsersÀrees temàtiques de la UPC::Enginyeria dels materialsThe project is aimed at investigating the effect of laser surface modification of dental-grade zirconia (3Y-TZP) to guide cellular behaviour. A nanosecond laser was employed to fabricate groove patterns on the surface of 3Y-TZP, yielding three different topographies according to the groove periodicity (30, 50 and 100µm). The resulting topography, microstructure, hardness and hydrothermal degradation resistance of the modified zirconia was assessed by means of advanced characterization techniques. A cellular study was conducted to evaluate the behaviour of human mesenchymal stem cells on the patterned samples in terms of adhesion and cell morphology. The results showed grooves of approximately 1.7µm heigh with pronounced pile-up due to the melting and re-solidification of the material. The phase analysis revealed that no phase transformation is induced during the laser modification; however, a non-homogeneous monoclinic phase distribution was observed on the patterned surfaces after hydrothermal degradation. Finally, all the patterned surfaces allowed cell attachment, increased cell area and favoured cell elongation and alignment in the direction of the laser patterns.Sociedad Española de Materiales20222022-04-0520222022-07-04journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://hdl.handle.net/2117/369461reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/3694612026-05-27T15:37:01Z
dc.title.none.fl_str_mv Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
title Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
spellingShingle Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
García de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139
Zirconium
Lasers
Zirconia
Laser patterning
Topography
Phase transformation
Hydrothermal degradation
Cell adhesion
Zirconi
Làsers
Àrees temàtiques de la UPC::Enginyeria dels materials
title_short Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
title_full Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
title_fullStr Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
title_full_unstemmed Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
title_sort Laser-assisted surface modification of zirconia-based materials to guide osteoblast responses for dental applications
dc.creator.none.fl_str_mv García de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139
Roa Rovira, Joan Josep|||0000-0002-7440-0766
Mas Moruno, Carlos|||0000-0001-8337-0872
author García de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139
author_facet García de Albéniz López de Aberasturi, Nerea|||0000-0003-0227-4139
Roa Rovira, Joan Josep|||0000-0002-7440-0766
Mas Moruno, Carlos|||0000-0001-8337-0872
author_role author
author2 Roa Rovira, Joan Josep|||0000-0002-7440-0766
Mas Moruno, Carlos|||0000-0001-8337-0872
author2_role author
author
dc.subject.none.fl_str_mv Zirconium
Lasers
Zirconia
Laser patterning
Topography
Phase transformation
Hydrothermal degradation
Cell adhesion
Zirconi
Làsers
Àrees temàtiques de la UPC::Enginyeria dels materials
topic Zirconium
Lasers
Zirconia
Laser patterning
Topography
Phase transformation
Hydrothermal degradation
Cell adhesion
Zirconi
Làsers
Àrees temàtiques de la UPC::Enginyeria dels materials
description The project is aimed at investigating the effect of laser surface modification of dental-grade zirconia (3Y-TZP) to guide cellular behaviour. A nanosecond laser was employed to fabricate groove patterns on the surface of 3Y-TZP, yielding three different topographies according to the groove periodicity (30, 50 and 100µm). The resulting topography, microstructure, hardness and hydrothermal degradation resistance of the modified zirconia was assessed by means of advanced characterization techniques. A cellular study was conducted to evaluate the behaviour of human mesenchymal stem cells on the patterned samples in terms of adhesion and cell morphology. The results showed grooves of approximately 1.7µm heigh with pronounced pile-up due to the melting and re-solidification of the material. The phase analysis revealed that no phase transformation is induced during the laser modification; however, a non-homogeneous monoclinic phase distribution was observed on the patterned surfaces after hydrothermal degradation. Finally, all the patterned surfaces allowed cell attachment, increased cell area and favoured cell elongation and alignment in the direction of the laser patterns.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-04-05
2022
2022-07-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/369461
url https://hdl.handle.net/2117/369461
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Sociedad Española de Materiales
publisher.none.fl_str_mv Sociedad Española de Materiales
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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