Iodine Intake, Thyroid Function and Neurodevelopmental Outcome in Preterm Infants from 24 to 30 Weeks Gestation

Neonatal hypothyroxinemia has been linked to increased risk of neurodevelopmental disabilities. The objective is to evaluate iodine status and thyroid function of premature babies and to correlate the data with neurodevelopment at 2 years. 67 infants were enrolled. Gestational age in weeks (27.5±0.2...

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Detalles Bibliográficos
Autores: Ares, S, Sáenz-Rico de Santiago, María Belén, Diez, JMD, Bernal, J
Tipo de recurso: artículo
Fecha de publicación:2016
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/100144
Acceso en línea:https://hdl.handle.net/20.500.14352/100144
Access Level:acceso abierto
Palabra clave:612.65-053.2
37.012
159.922.7
Hypothyroxinemia
Preterm infants
Thyroid
Neurodevelopment
Iodine deficiency
Ciencias Biomédicas
Ciencias Sociales
Métodos de investigación en educación
32 Ciencias Médicas
58 Pedagogía
5801 Teoría y Métodos Educativos
Descripción
Sumario:Neonatal hypothyroxinemia has been linked to increased risk of neurodevelopmental disabilities. The objective is to evaluate iodine status and thyroid function of premature babies and to correlate the data with neurodevelopment at 2 years. 67 infants were enrolled. Gestational age in weeks (27.5±0.2) and weight (986.5±30.8 gr). Breast milk contained 25.8±1.4 µg I/100 ml and formulae were 10 µg I /100 ml. Only 20% of the babies had an iodine intake above 30 µg I/Kg. Thyroid hormones were negatively correlated by a low iodine intake. There were differences in neurodevelopmental indexes with lower iodine intake. Iodine intake should be ensured during the neonatal period by breast milk or preterm formulae with high iodine content.