Monoglyceride surfactants from arginine: synthesis and biological properties

9 pages, 9 figures, 5 tables.-- Printed version published Nov 2004.

Bibliographic Details
Authors: Pérez, Lourdes, Pinazo Gassol, Aurora, García Ramón, María Teresa, Morán, María del Carmen, Infante, María Rosa
Format: article
Publication Date:2004
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/18380
Online Access:http://hdl.handle.net/10261/18380
Access Level:Open access
Keyword:Monoglyceride surfactants
Dicationic arginine based surfactants
1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl
Antimicrobial properties
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spelling Monoglyceride surfactants from arginine: synthesis and biological propertiesPérez, LourdesPinazo Gassol, AuroraGarcía Ramón, María TeresaMorán, María del CarmenInfante, María RosaMonoglyceride surfactantsDicationic arginine based surfactants1-acyl-3-O-(L-arginyl)-rac-glycerol·2HClAntimicrobial properties9 pages, 9 figures, 5 tables.-- Printed version published Nov 2004.A novel family of dicationic arginine-monoglyceride surfactants, 1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl, was synthesised and characterised. They have one alkyl chain of with length in the range of C10–C14 attached to the glycerol though esters bonds and a dicationic polar head from the arginine. Structurally they can be regarded as analogues of the monoglycerides, widely used as emulsifiers in the food and in the pharmaceutical industry. The introduction of the basic amino acid arginine into the monoglycerides increases the solubility of these compounds and improves their antimicrobial activity. Moreover, the acute toxicity of these surfactants against Daphnia magna is clearly lower than the toxicity reported for conventional cationic surfactants.Financial support from the Spanish CYCIT, ref. PPQ2003-01834.Peer reviewedRoyal Society of Chemistry (UK)200920092004info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501660850 bytesapplication/pdfhttp://hdl.handle.net/10261/18380reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://dx.doi.org/10.1039/b405733cinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/183802026-05-22T06:33:51Z
dc.title.none.fl_str_mv Monoglyceride surfactants from arginine: synthesis and biological properties
title Monoglyceride surfactants from arginine: synthesis and biological properties
spellingShingle Monoglyceride surfactants from arginine: synthesis and biological properties
Pérez, Lourdes
Monoglyceride surfactants
Dicationic arginine based surfactants
1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl
Antimicrobial properties
title_short Monoglyceride surfactants from arginine: synthesis and biological properties
title_full Monoglyceride surfactants from arginine: synthesis and biological properties
title_fullStr Monoglyceride surfactants from arginine: synthesis and biological properties
title_full_unstemmed Monoglyceride surfactants from arginine: synthesis and biological properties
title_sort Monoglyceride surfactants from arginine: synthesis and biological properties
dc.creator.none.fl_str_mv Pérez, Lourdes
Pinazo Gassol, Aurora
García Ramón, María Teresa
Morán, María del Carmen
Infante, María Rosa
author Pérez, Lourdes
author_facet Pérez, Lourdes
Pinazo Gassol, Aurora
García Ramón, María Teresa
Morán, María del Carmen
Infante, María Rosa
author_role author
author2 Pinazo Gassol, Aurora
García Ramón, María Teresa
Morán, María del Carmen
Infante, María Rosa
author2_role author
author
author
author
dc.subject.none.fl_str_mv Monoglyceride surfactants
Dicationic arginine based surfactants
1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl
Antimicrobial properties
topic Monoglyceride surfactants
Dicationic arginine based surfactants
1-acyl-3-O-(L-arginyl)-rac-glycerol·2HCl
Antimicrobial properties
description 9 pages, 9 figures, 5 tables.-- Printed version published Nov 2004.
publishDate 2004
dc.date.none.fl_str_mv 2004
2009
2009
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/18380
url http://hdl.handle.net/10261/18380
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://dx.doi.org/10.1039/b405733c
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 660850 bytes
application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry (UK)
publisher.none.fl_str_mv Royal Society of Chemistry (UK)
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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