Efficient space and time multicomparison of genomes

The comparison of genomes is based on substrings, called MUMs, that appear only once in each genome and are maximal. The set of MUMs determines the skeleton from which a global comparison can be established. The search of MUMs is handled with Suffix trees which are those trees that store all suffixe...

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Bibliographic Details
Authors: Messeguer Peypoch, Xavier|||0000-0001-7430-4857, Huerta, Mario
Format: report
Publication Date:2003
Country:España
Institution:Universitat Politècnica de Catalunya (UPC)
Repository:UPCommons. Portal del coneixement obert de la UPC
Language:English
OAI Identifier:oai:upcommons.upc.edu:2117/97409
Online Access:https://hdl.handle.net/2117/97409
Access Level:Open access
Keyword:Genomes comparison
MuMs
Suffix trees
Pattern matching
Àrees temàtiques de la UPC::Informàtica
Description
Summary:The comparison of genomes is based on substrings, called MUMs, that appear only once in each genome and are maximal. The set of MUMs determines the skeleton from which a global comparison can be established. The search of MUMs is handled with Suffix trees which are those trees that store all suffixes of a given sequence. The searching algorithm builds a generalized suffixtree for each pair and finds the MUMs between them.