Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia

It is not known whether rainfall increases the risk of sporadic cases of Legionella pneumonia. We sought to test this hypothesis in a prospective observational cohort study of non-immunosuppressed adults hospitalized for community-acquired pneumonia (1995-2011). Cases with Legionella pneumonia were...

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Authors: Garcia Vidal, Carolina, Labori, Maria, Viasus, Diego, Simonetti, Antonella Francesca, Garcia Somoza, Dolors, Dorca i Sargatal, Jordi, Gudiol i Munté, Francesc, Carratalà, Jordi
Format: article
Status:Published version
Publication Date:2013
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/53490
Online Access:https://hdl.handle.net/2445/53490
Access Level:Open access
Keyword:Pneumònia
Legionel·la
Pneumonia
Legionella
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spelling Rainfall is a risk factor for sporadic cases of Legionella pneumophila PneumoniaGarcia Vidal, CarolinaLabori, MariaViasus, DiegoSimonetti, Antonella FrancescaGarcia Somoza, DolorsDorca i Sargatal, JordiGudiol i Munté, FrancescCarratalà, JordiPneumòniaLegionel·laPneumoniaLegionellaIt is not known whether rainfall increases the risk of sporadic cases of Legionella pneumonia. We sought to test this hypothesis in a prospective observational cohort study of non-immunosuppressed adults hospitalized for community-acquired pneumonia (1995-2011). Cases with Legionella pneumonia were compared with those with non-Legionella pneumonia. Using daily rainfall data obtained from the regional meteorological service we examined patterns of rainfall over the days prior to admission in each study group. Of 4168 patients, 231 (5.5%) had Legionella pneumonia. The diagnosis was based on one or more of the following: sputum (41 cases), antigenuria (206) and serology (98). Daily rainfall average was 0.556 liters/m2 in the Legionella pneumonia group vs. 0.328 liters/m2 for non-Legionella pneumonia cases (p = 0.04). A ROC curve was plotted to compare the incidence of Legionella pneumonia and the weighted median rainfall. The cut-off point was 0.42 (AUC 0.54). Patients who were admitted to hospital with a prior weighted median rainfall higher than 0.42 were more likely to have Legionella pneumonia (OR 1.35; 95% CI 1.02-1.78; p = .03). Spearman Rho correlations revealed a relationship between Legionella pneumonia and rainfall average during each two-week reporting period (0.14; p = 0.003). No relationship was found between rainfall average and non-Legionella pneumonia cases (−0.06; p = 0.24). As a conclusion, rainfall is a significant risk factor for sporadic Legionella pneumonia. Physicians should carefully consider Legionella pneumonia when selecting diagnostic tests and antimicrobial therapy for patients presenting with CAP after periods of rainfall.Public Library of Science (PLoS)2014201420132014info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion5 p.application/pdfhttps://hdl.handle.net/2445/53490Articles publicats en revistes (Ciències Clíniques)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0061036PLoS One, 2013, vol. 8, num. 4, p. 1-5http://dx.doi.org/10.1371/journal.pone.0061036cc-by (c) Garcia Vidal, Carolina et al., 2013http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/534902026-05-29T05:05:01Z
dc.title.none.fl_str_mv Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
title Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
spellingShingle Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
Garcia Vidal, Carolina
Pneumònia
Legionel·la
Pneumonia
Legionella
title_short Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
title_full Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
title_fullStr Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
title_full_unstemmed Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
title_sort Rainfall is a risk factor for sporadic cases of Legionella pneumophila Pneumonia
dc.creator.none.fl_str_mv Garcia Vidal, Carolina
Labori, Maria
Viasus, Diego
Simonetti, Antonella Francesca
Garcia Somoza, Dolors
Dorca i Sargatal, Jordi
Gudiol i Munté, Francesc
Carratalà, Jordi
author Garcia Vidal, Carolina
author_facet Garcia Vidal, Carolina
Labori, Maria
Viasus, Diego
Simonetti, Antonella Francesca
Garcia Somoza, Dolors
Dorca i Sargatal, Jordi
Gudiol i Munté, Francesc
Carratalà, Jordi
author_role author
author2 Labori, Maria
Viasus, Diego
Simonetti, Antonella Francesca
Garcia Somoza, Dolors
Dorca i Sargatal, Jordi
Gudiol i Munté, Francesc
Carratalà, Jordi
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Pneumònia
Legionel·la
Pneumonia
Legionella
topic Pneumònia
Legionel·la
Pneumonia
Legionella
description It is not known whether rainfall increases the risk of sporadic cases of Legionella pneumonia. We sought to test this hypothesis in a prospective observational cohort study of non-immunosuppressed adults hospitalized for community-acquired pneumonia (1995-2011). Cases with Legionella pneumonia were compared with those with non-Legionella pneumonia. Using daily rainfall data obtained from the regional meteorological service we examined patterns of rainfall over the days prior to admission in each study group. Of 4168 patients, 231 (5.5%) had Legionella pneumonia. The diagnosis was based on one or more of the following: sputum (41 cases), antigenuria (206) and serology (98). Daily rainfall average was 0.556 liters/m2 in the Legionella pneumonia group vs. 0.328 liters/m2 for non-Legionella pneumonia cases (p = 0.04). A ROC curve was plotted to compare the incidence of Legionella pneumonia and the weighted median rainfall. The cut-off point was 0.42 (AUC 0.54). Patients who were admitted to hospital with a prior weighted median rainfall higher than 0.42 were more likely to have Legionella pneumonia (OR 1.35; 95% CI 1.02-1.78; p = .03). Spearman Rho correlations revealed a relationship between Legionella pneumonia and rainfall average during each two-week reporting period (0.14; p = 0.003). No relationship was found between rainfall average and non-Legionella pneumonia cases (−0.06; p = 0.24). As a conclusion, rainfall is a significant risk factor for sporadic Legionella pneumonia. Physicians should carefully consider Legionella pneumonia when selecting diagnostic tests and antimicrobial therapy for patients presenting with CAP after periods of rainfall.
publishDate 2013
dc.date.none.fl_str_mv 2013
2014
2014
2014
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/53490
url https://hdl.handle.net/2445/53490
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0061036
PLoS One, 2013, vol. 8, num. 4, p. 1-5
http://dx.doi.org/10.1371/journal.pone.0061036
dc.rights.none.fl_str_mv cc-by (c) Garcia Vidal, Carolina et al., 2013
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Garcia Vidal, Carolina et al., 2013
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5 p.
application/pdf
dc.publisher.none.fl_str_mv Public Library of Science (PLoS)
publisher.none.fl_str_mv Public Library of Science (PLoS)
dc.source.none.fl_str_mv Articles publicats en revistes (Ciències Clíniques)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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