Enantioselective Syntehsis of Alkaloids from Phenylglycinol-derived lactams

This review is focused on recent synthetic achievements and ongoing work in our laboratory using phenylglycinol-derived oxazolopiperidone lactams as starting materials for the enantioselective synthesis of piperidine-containing alkaloids: madangamines, 2,5-disubstituted decahydroquinoline and 1-subs...

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Detalles Bibliográficos
Autores: Amat Tusón, Mercedes, Llor Brunés, Núria, Griera Farres, Rosa, Pérez Bosch, Maria, Bosch Cartes, Joan
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2011
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/172794
Acceso en línea:https://hdl.handle.net/2445/172794
Access Level:acceso abierto
Palabra clave:Alcaloides
Lactames
Síntesi orgànica
Alkaloids
Lactams
Organic synthesis
Descripción
Sumario:This review is focused on recent synthetic achievements and ongoing work in our laboratory using phenylglycinol-derived oxazolopiperidone lactams as starting materials for the enantioselective synthesis of piperidine-containing alkaloids: madangamines, 2,5-disubstituted decahydroquinoline and 1-substituted tetrahydroisoquinoline alkaloids, the indole alkaloids 20S- and 20R-dihydrocleavamine and quebrachamine, and indole alkaloids of the uleine and silicine groups. Keywords: alkaloids, piperidine, indole, lactams, total synthesis, phenylglycinol.