Articulating the 'stem cell niche' paradigm through the lens of non-model aquatic invertebrates

Stem cells (SCs) in vertebrates typically reside in "stem cell niches" (SCNs), morphologically restricted tissue microenvironments that are important for SC survival and proliferation. SCNs are broadly defined by properties including physical location, but in contrast to vertebrates and ot...

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Detalles Bibliográficos
Autores: Martínez Serra, Pedro, Ballarin, L., Ereskovsky, A. V., Gazave, E., Hobmayer, B., Manni, L., Rottinger, E., Sprecher, Simon G., Tiozzo, S., Varela-Coelho, A., Rinkevich, Baruch
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/186042
Acceso en línea:https://hdl.handle.net/2445/186042
Access Level:acceso abierto
Palabra clave:Cèl·lules mare
Organismes aquàtics
Stem cells
Aquatic organisms
Descripción
Sumario:Stem cells (SCs) in vertebrates typically reside in "stem cell niches" (SCNs), morphologically restricted tissue microenvironments that are important for SC survival and proliferation. SCNs are broadly defined by properties including physical location, but in contrast to vertebrates and other "model" organisms, aquatic invertebrate SCs do not have clearly documented niche outlines or properties. Life strategies such as regeneration or asexual reproduction may have conditioned the niche architectural variability in aquatic or marine animal groups. By both establishing the invertebrates SCNs as independent types, yet allowing inclusiveness among them, the comparative analysis will allow the future functional characterization of SCNs.