Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a large hospital in Spain. Of the 578 participants recruited from 28 March to 9 A...

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Detalles Bibliográficos
Autores: García-Basteiro, Alberto L., Moncunill Piñas, Gemma, Tortajada, Marta, Vidal, Marta, Guinovart, Caterina, Jiménez, Alfons, Santano, Rebeca, Sanz, Sergi, Méndez, Susana, Llupià Garcia, Anna, Aguilar, Ruth, Alonso, Selena, Barrios, Diana, Carolis, Carlo, Cisteró, Pau, Chóliz, Eugenia, Cruz, Angeline, Fochs, Silvia, Jairoce, Chenjerai Tobias Sixpence, Hecht, Jochen, Lamoglia-Puig, Montserrat, Martínez Yoldi, Miguel Julián, Mitchell, Robert Andrew, Ortega, Natalia, Pey, Nuria, Puyol, Laura, Ribes, Marta, Rosell, Neus, Sotomayor, Patricia, Torres, Sara, Williams, Sara, Barroso, Sonia, Vilella i Morató, Anna, Muñoz Gutiérrez, José, Trilla García, Antoni, Varela, Pilar, Mayor Aparicio, Alfredo Gabriel, Dobaño, Carlota, 1969-
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/176139
Acceso en línea:https://hdl.handle.net/2445/176139
Access Level:acceso abierto
Palabra clave:SARS-CoV-2
Immunoglobulines
Epidemiologia
Immunoglobulins
Epidemiology
Descripción
Sumario:Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. This study aims at estimating the seroprevalence against SARS-CoV-2 in a random sample of HCW from a large hospital in Spain. Of the 578 participants recruited from 28 March to 9 April 2020, 54 (9.3%, 95% CI: 7.1-12.0) were seropositive for IgM and/or IgG and/or IgA against SARS-CoV-2. The cumulative prevalence of SARS-CoV-2 infection (presence of antibodies or past or current positive rRT-PCR) was 11.2% (65/578, 95% CI: 8.8-14.1). Among those with evidence of past or current infection, 40.0% (26/65) had not been previously diagnosed with COVID-19. Here we report a relatively low seroprevalence of antibodies among HCW at the peak of the COVID-19 epidemic in Spain. A large proportion of HCW with past or present infection had not been previously diagnosed with COVID-19, which calls for active periodic rRT-PCR testing in hospital settings.

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