Transcriptional and epigenetic changes during tomato yellow leaf curl virus infection in tomato

Geminiviruses are DNA plant viruses that cause highly damaging diseases affecting crops worldwide. During the infection, geminiviruses hijack cellular processes, suppress plant defenses, and cause a massive reprogramming of the infected cells leading to major changes in the whole plant homeostasis....

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Detalles Bibliográficos
Autores: Romero-Rodríguez, Beatriz, Petek, Marko, Jiao, Chen, Križnik, Maja, Zagorščak, Maja, Fei, Zhangjun, Bejarano, Eduardo R, Gruden, Kristina, Castillo, Araceli G.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/370745
Acceso en línea:http://hdl.handle.net/10261/370745
https://api.elsevier.com/content/abstract/scopus_id/85179911330
Access Level:acceso abierto
Palabra clave:DNA methylation
Epigenome
Geminivirus
Gene silencing
Immune system
TYLCV
Tomato
Transcriptome
miRNA
phasiRNA
Descripción
Sumario:Geminiviruses are DNA plant viruses that cause highly damaging diseases affecting crops worldwide. During the infection, geminiviruses hijack cellular processes, suppress plant defenses, and cause a massive reprogramming of the infected cells leading to major changes in the whole plant homeostasis. The advances in sequencing technologies allow the simultaneous analysis of multiple aspects of viral infection at a large scale, generating new insights into the molecular mechanisms underlying plant-virus interactions. However, an integrative study of the changes in the host transcriptome, small RNA profile and methylome during a geminivirus infection has not been performed yet. Using a time-scale approach, we aim to decipher the gene regulation in tomato in response to the infection with the geminivirus, tomato yellow leaf curl virus (TYLCV).