Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers

7 p.

Detalles Bibliográficos
Autores: Reinares Ortiz, Javier, Pérez Serrano, Jorge|||0000-0002-4870-8978, González Rubio, Juana María, González Camacho, Fernando
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/67804
Acceso en línea:http://hdl.handle.net/10017/67804
https://dx.doi.org/10.3390/microorganisms12112139
Access Level:acceso abierto
Palabra clave:Legionnaires" disease
Humidifier
Sporadic case
Legionella pneumophila
Medicina
Biología
Biology
Medicine
id ES_7fbb204d6fa65fbefa0ae1ce445556ee
oai_identifier_str oai:ebuah.uah.es:10017/67804
network_acronym_str ES
network_name_str España
repository_id_str
spelling Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiersReinares Ortiz, JavierPérez Serrano, Jorge|||0000-0002-4870-8978González Rubio, Juana MaríaGonzález Camacho, FernandoLegionnaires" diseaseHumidifierSporadic caseLegionella pneumophilaMedicinaBiologíaBiologyMedicine7 p.Two sporadic cases of legionellosis occurring in consecutive years were confirmed by positive antigenuria to Legionella pneumophila serogroup 1 in individuals with limited mobility who were confined to their homes. Both cases had a history of using ultrasonic humidifiers and of low exposure to other possible sources of infection. This study was conducted through an expanded epidemiological survey and home inspection. Samples were collected from domestic hot water and humidifiers. Environmental isolates were characterised by immunoagglutination and immunofluorescence. The Dresden panel is employed for the determination of groups and subgroups of serogroup 1. The amoebae were isolated by water filtration and subsequent cultivation of the filters. Identification of the isolates was conducted through the sequencing of PCR products. In both cases, epidemiological studies identified the ultrasonic humidifiers as the probable source of infection. The presence of Legionella pneumophila was confirmed in the sanitary water installation and in the humidifiers, where high values of Legionella pneumophila serogroup 1 counts were also obtained. The isolates were characterised as Olda Oxford and Olda OLDA. Furthermore, in addition to the Legionella isolates, the presence of Vermamoeba vermiformis was also identified in samples obtained from domestic hot water and humidifiers in one of the residential addresses under investigation. It has been demonstrated that humidifiers can act as an amplification mechanism for pathogenic microorganisms when they are not cleaned and maintained correctly. This can pose a health danger, especially to people with previous respiratory pathologies, the immunosuppressed, and the elderly. Therefore, it is of the utmost importance that professionals who recommend the therapeutic use of this equipment should issue warnings regarding the importance of its correct use, cleaning, and disinfection. Finally, humidifiers should be considered in epidemiological surveys and in the study of sporadic cases.Instituto de Salud Carlos IIIMDPI20242024-10-25journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/67804https://dx.doi.org/10.3390/microorganisms12112139reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)InglésengISCIII Not available AESI-2022 MPY 341%2F22open accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/678042026-06-18T11:13:07Z
dc.title.none.fl_str_mv Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
title Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
spellingShingle Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
Reinares Ortiz, Javier
Legionnaires" disease
Humidifier
Sporadic case
Legionella pneumophila
Medicina
Biología
Biology
Medicine
title_short Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
title_full Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
title_fullStr Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
title_full_unstemmed Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
title_sort Two sporadic cases of Legionellosis associated with the use of domestic ultrasonic humidifiers
dc.creator.none.fl_str_mv Reinares Ortiz, Javier
Pérez Serrano, Jorge|||0000-0002-4870-8978
González Rubio, Juana María
González Camacho, Fernando
author Reinares Ortiz, Javier
author_facet Reinares Ortiz, Javier
Pérez Serrano, Jorge|||0000-0002-4870-8978
González Rubio, Juana María
González Camacho, Fernando
author_role author
author2 Pérez Serrano, Jorge|||0000-0002-4870-8978
González Rubio, Juana María
González Camacho, Fernando
author2_role author
author
author
dc.subject.none.fl_str_mv Legionnaires" disease
Humidifier
Sporadic case
Legionella pneumophila
Medicina
Biología
Biology
Medicine
topic Legionnaires" disease
Humidifier
Sporadic case
Legionella pneumophila
Medicina
Biología
Biology
Medicine
description 7 p.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-10-25
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10017/67804
https://dx.doi.org/10.3390/microorganisms12112139
url http://hdl.handle.net/10017/67804
https://dx.doi.org/10.3390/microorganisms12112139
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv ISCIII Not available AESI-2022 MPY 341%2F22
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:e_Buah Biblioteca Digital Universidad de Alcalá
instname:Universidad de Alcalá (UAH)
instname_str Universidad de Alcalá (UAH)
reponame_str e_Buah Biblioteca Digital Universidad de Alcalá
collection e_Buah Biblioteca Digital Universidad de Alcalá
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869411846434324480
score 15,81155

Similares en LA Referencia