The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider
Spiders (Araneae) have a diverse spectrum of morphologies, behaviors, and physiologies. Attempts to understand the genomic-basis of this diversity are often hindered by their large, heterozygous, and AT-rich genomes with high repeat content resulting in highly fragmented, poor-quality assemblies. As...
| Autores: | , , , , , , , , , |
|---|---|
| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/195746 |
| Acesso em linha: | https://hdl.handle.net/2445/195746 |
| Access Level: | acceso abierto |
| Palavra-chave: | Aranyes Artròpodes Hawaii Spiders Arthropoda Hawai |
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The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spiderCerca, JoséArmstrong, Ellie E.Vizueta Moraga, JoelFernández, RosaDimitrov, DimitarPetersen, BentProst, StefanRozas Liras, Julio A.Petrov, DmitriGillespie, Rosemary G.AranyesArtròpodesHawaiiSpidersArthropodaHawaiSpiders (Araneae) have a diverse spectrum of morphologies, behaviors, and physiologies. Attempts to understand the genomic-basis of this diversity are often hindered by their large, heterozygous, and AT-rich genomes with high repeat content resulting in highly fragmented, poor-quality assemblies. As a result, the key attributes of spider genomes, including gene family evolution, repeat content, and gene function, remain poorly understood. Here, we used Illumina and Dovetail Chicago technologies to sequence the genome of the long-jawed spider Tetragnatha kauaiensis, producing an assembly distributed along 3,925 scaffolds with an N50 of ∼2 Mb. Using comparative genomics tools, we explore genome evolution across available spider assemblies. Our findings suggest that the previously reported and vast genome size variation in spiders is linked to the different representation and number of transposable elements. Using statistical tools to uncover gene-family level evolution, we find expansions associated with the sensory perception of taste, immunity, and metabolism. In addition, we report strikingly different histories of chemosensory, venom, and silk gene families, with the first two evolving much earlier, affected by the ancestral whole genome duplication in Arachnopulmonata (∼450 Ma) and exhibiting higher numbers. Together, our findings reveal that spider genomes are highly variable and that genomic novelty may have been driven by the burst of an ancient whole genome duplication, followed by gene family and transposable element expansion.Oxford University Press2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/195746Articles publicats en revistes (Genètica, Microbiologia i Estadística)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1093/gbe/evab262Genome Biology and Evolution, 2021, vol. 13, num. 12, p. 1-17https://doi.org/10.1093/gbe/evab262cc-by-nc (c) Cerca, José et al., 2021https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1957462026-05-27T06:46:51Z |
| dc.title.none.fl_str_mv |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| title |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| spellingShingle |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider Cerca, José Aranyes Artròpodes Hawaii Spiders Arthropoda Hawai |
| title_short |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| title_full |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| title_fullStr |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| title_full_unstemmed |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| title_sort |
The Tetragnatha kauaiensis genome sheds light on the origins of genomic novelty in spider |
| dc.creator.none.fl_str_mv |
Cerca, José Armstrong, Ellie E. Vizueta Moraga, Joel Fernández, Rosa Dimitrov, Dimitar Petersen, Bent Prost, Stefan Rozas Liras, Julio A. Petrov, Dmitri Gillespie, Rosemary G. |
| author |
Cerca, José |
| author_facet |
Cerca, José Armstrong, Ellie E. Vizueta Moraga, Joel Fernández, Rosa Dimitrov, Dimitar Petersen, Bent Prost, Stefan Rozas Liras, Julio A. Petrov, Dmitri Gillespie, Rosemary G. |
| author_role |
author |
| author2 |
Armstrong, Ellie E. Vizueta Moraga, Joel Fernández, Rosa Dimitrov, Dimitar Petersen, Bent Prost, Stefan Rozas Liras, Julio A. Petrov, Dmitri Gillespie, Rosemary G. |
| author2_role |
author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Aranyes Artròpodes Hawaii Spiders Arthropoda Hawai |
| topic |
Aranyes Artròpodes Hawaii Spiders Arthropoda Hawai |
| description |
Spiders (Araneae) have a diverse spectrum of morphologies, behaviors, and physiologies. Attempts to understand the genomic-basis of this diversity are often hindered by their large, heterozygous, and AT-rich genomes with high repeat content resulting in highly fragmented, poor-quality assemblies. As a result, the key attributes of spider genomes, including gene family evolution, repeat content, and gene function, remain poorly understood. Here, we used Illumina and Dovetail Chicago technologies to sequence the genome of the long-jawed spider Tetragnatha kauaiensis, producing an assembly distributed along 3,925 scaffolds with an N50 of ∼2 Mb. Using comparative genomics tools, we explore genome evolution across available spider assemblies. Our findings suggest that the previously reported and vast genome size variation in spiders is linked to the different representation and number of transposable elements. Using statistical tools to uncover gene-family level evolution, we find expansions associated with the sensory perception of taste, immunity, and metabolism. In addition, we report strikingly different histories of chemosensory, venom, and silk gene families, with the first two evolving much earlier, affected by the ancestral whole genome duplication in Arachnopulmonata (∼450 Ma) and exhibiting higher numbers. Together, our findings reveal that spider genomes are highly variable and that genomic novelty may have been driven by the burst of an ancient whole genome duplication, followed by gene family and transposable element expansion. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/2445/195746 |
| url |
https://hdl.handle.net/2445/195746 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Reproducció del document publicat a: https://doi.org/10.1093/gbe/evab262 Genome Biology and Evolution, 2021, vol. 13, num. 12, p. 1-17 https://doi.org/10.1093/gbe/evab262 |
| dc.rights.none.fl_str_mv |
cc-by-nc (c) Cerca, José et al., 2021 https://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess |
| rights_invalid_str_mv |
cc-by-nc (c) Cerca, José et al., 2021 https://creativecommons.org/licenses/by-nc/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Oxford University Press |
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Oxford University Press |
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Articles publicats en revistes (Genètica, Microbiologia i Estadística) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona |
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Universidad de Barcelona |
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Dipòsit Digital de la UB |
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Dipòsit Digital de la UB |
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