Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes

The clinical application of phentolamine mesylate (PM) as an anaesthetic reversal agent has been documented in the paediatric population and in conservative dentistry, but no studies have been conducted regarding dental implant surgery. A prospective randomised study was conducted on 60 patients eli...

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Autores: Vintanel Moreno, Clara, Martínez González, José María, Martínez Rodríguez, Natalia, Meniz García, Cristina María, Leco Berrocal, María Isabel
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/93644
Acceso en línea:https://hdl.handle.net/20.500.14352/93644
Access Level:acceso abierto
Palabra clave:616.314-089.843
615.06
Phentolamine mesylate
Dental implants
Haemodynamic changes
Adverse effects
Satisfaction
Implantes dentales
Toxicología (Farmacia)
3213.13 Ortodoncia-Estomatología
3209.03 Evaluación de Medicamentos
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oai_identifier_str oai:docta.ucm.es:20.500.14352/93644
network_acronym_str ES
network_name_str España
repository_id_str
spelling Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changesVintanel Moreno, ClaraMartínez González, José MaríaMartínez Rodríguez, NataliaMeniz García, Cristina MaríaLeco Berrocal, María Isabel616.314-089.843615.06Phentolamine mesylateDental implantsHaemodynamic changesAdverse effectsSatisfactionImplantes dentalesToxicología (Farmacia)3213.13 Ortodoncia-Estomatología3209.03 Evaluación de MedicamentosThe clinical application of phentolamine mesylate (PM) as an anaesthetic reversal agent has been documented in the paediatric population and in conservative dentistry, but no studies have been conducted regarding dental implant surgery. A prospective randomised study was conducted on 60 patients eligible for mandibular implant treatment, randomly divided between a control group (CG) and an experimental group (EG), to whom PM was administered. Haemodynamic changes, adverse effects and patient satisfaction were assessed. No statistically significant differences in haemodynamic changes and postoperative pain were found between CG and EG (p < 0.05), except for systolic blood pressure (SBP), which increased slightly in EG, without posing a risk to patients. There were no differences in the occurrence of adverse effects between the two groups, except for greater difficulty in chewing and biting (p < 0.05) in CG and greater pain in the injection area (p = 0.043) in EG. Among EG patients, 83.3% reported that they would request PM again for future dental treatment. The use of PM offers an alternative to implant surgery, thereby increasing patients’ quality of life without increasing the risks.MDPIUniversidad Complutense de Madrid20212021-08-2820212021-08-28journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/93644reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/936442026-06-02T12:44:21Z
dc.title.none.fl_str_mv Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
title Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
spellingShingle Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
Vintanel Moreno, Clara
616.314-089.843
615.06
Phentolamine mesylate
Dental implants
Haemodynamic changes
Adverse effects
Satisfaction
Implantes dentales
Toxicología (Farmacia)
3213.13 Ortodoncia-Estomatología
3209.03 Evaluación de Medicamentos
title_short Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
title_full Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
title_fullStr Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
title_full_unstemmed Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
title_sort Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
dc.creator.none.fl_str_mv Vintanel Moreno, Clara
Martínez González, José María
Martínez Rodríguez, Natalia
Meniz García, Cristina María
Leco Berrocal, María Isabel
author Vintanel Moreno, Clara
author_facet Vintanel Moreno, Clara
Martínez González, José María
Martínez Rodríguez, Natalia
Meniz García, Cristina María
Leco Berrocal, María Isabel
author_role author
author2 Martínez González, José María
Martínez Rodríguez, Natalia
Meniz García, Cristina María
Leco Berrocal, María Isabel
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 616.314-089.843
615.06
Phentolamine mesylate
Dental implants
Haemodynamic changes
Adverse effects
Satisfaction
Implantes dentales
Toxicología (Farmacia)
3213.13 Ortodoncia-Estomatología
3209.03 Evaluación de Medicamentos
topic 616.314-089.843
615.06
Phentolamine mesylate
Dental implants
Haemodynamic changes
Adverse effects
Satisfaction
Implantes dentales
Toxicología (Farmacia)
3213.13 Ortodoncia-Estomatología
3209.03 Evaluación de Medicamentos
description The clinical application of phentolamine mesylate (PM) as an anaesthetic reversal agent has been documented in the paediatric population and in conservative dentistry, but no studies have been conducted regarding dental implant surgery. A prospective randomised study was conducted on 60 patients eligible for mandibular implant treatment, randomly divided between a control group (CG) and an experimental group (EG), to whom PM was administered. Haemodynamic changes, adverse effects and patient satisfaction were assessed. No statistically significant differences in haemodynamic changes and postoperative pain were found between CG and EG (p < 0.05), except for systolic blood pressure (SBP), which increased slightly in EG, without posing a risk to patients. There were no differences in the occurrence of adverse effects between the two groups, except for greater difficulty in chewing and biting (p < 0.05) in CG and greater pain in the injection area (p = 0.043) in EG. Among EG patients, 83.3% reported that they would request PM again for future dental treatment. The use of PM offers an alternative to implant surgery, thereby increasing patients’ quality of life without increasing the risks.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-08-28
2021
2021-08-28
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/93644
url https://hdl.handle.net/20.500.14352/93644
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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