Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies

The consumption of sweet beverages, including sugar-sweetened beverages (SSB), artificial-sweetened beverages (ASB) and fruit juices (FJ), is associated with the risk of different cardiometabolic diseases. It may also be linked to the development of certain types of tumors. We carried out a systemat...

Descripción completa

Detalles Bibliográficos
Autores: Llaha, Fjorida, Gil Lespinard, Mercedes, Unal, Pelin, Villasante, Izar de, Castañeda, Jazmín, Zamora-Ros, Raul
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/175990
Acceso en línea:https://hdl.handle.net/2445/175990
Access Level:acceso abierto
Palabra clave:Càncer
Sucre en l'organisme
Sucs de fruita
Cancer
Sugar in the body
Fruit juices
id ES_7ec4c9e5cab25be034d5fd1bcfd45f39
oai_identifier_str oai:diposit.ub.edu:2445/175990
network_acronym_str ES
network_name_str España
repository_id_str
spelling Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational StudiesLlaha, FjoridaGil Lespinard, MercedesUnal, PelinVillasante, Izar deCastañeda, JazmínZamora-Ros, RaulCàncerSucre en l'organismeSucs de fruitaCancerSugar in the bodyFruit juicesThe consumption of sweet beverages, including sugar-sweetened beverages (SSB), artificial-sweetened beverages (ASB) and fruit juices (FJ), is associated with the risk of different cardiometabolic diseases. It may also be linked to the development of certain types of tumors. We carried out a systematic review and meta-analysis of observational studies aimed at examining the association between sweet beverage intake and cancer risk. Suitable articles published up to June 2020 were sourced through PubMed, Web of Science and SCOPUS databases. Overall, 64 studies were identified, of which 27 were selected for the meta-analysis. This was performed by analyzing the multivariable-adjusted OR, RR or HR of the highest sweet beverage intake categories compared to the lowest one. Random effects showed significant positive association between SSB intake and breast (RR: 1.14, 95% CI: 1.01-1.30) and prostate cancer risk (RR: 1.18, 95% CI: 1.10-1.27) and also between FJs and prostate cancer risk (RR: 1.03, 95% CI: 1.01-1.05). Although the statistically significant threshold was not reached, there tended to be positive associations for the following: SSBs and colorectal and pancreatic cancer risk; FJs and breast, colorectal and pancreatic cancer risk; and ASBs and pancreatic cancer risk. This study recommends limiting sweet beverage consumption. Furthermore, we propose to establish a homogeneous classification of beverages and investigate them separately, to better understand their role in carcinogenesis.MDPI2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/175990Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/nu13020516Nutrients, 2021, vol. 13, num. 2https://doi.org/10.3390/nu13020516cc by (c) Llaha et al., 2021http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1759902026-05-27T06:46:51Z
dc.title.none.fl_str_mv Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
title Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
spellingShingle Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
Llaha, Fjorida
Càncer
Sucre en l'organisme
Sucs de fruita
Cancer
Sugar in the body
Fruit juices
title_short Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
title_full Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
title_fullStr Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
title_full_unstemmed Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
title_sort Consumption of Sweet Beverages and Cancer Risk. A Systematic Review and Meta-Analysis of Observational Studies
dc.creator.none.fl_str_mv Llaha, Fjorida
Gil Lespinard, Mercedes
Unal, Pelin
Villasante, Izar de
Castañeda, Jazmín
Zamora-Ros, Raul
author Llaha, Fjorida
author_facet Llaha, Fjorida
Gil Lespinard, Mercedes
Unal, Pelin
Villasante, Izar de
Castañeda, Jazmín
Zamora-Ros, Raul
author_role author
author2 Gil Lespinard, Mercedes
Unal, Pelin
Villasante, Izar de
Castañeda, Jazmín
Zamora-Ros, Raul
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Càncer
Sucre en l'organisme
Sucs de fruita
Cancer
Sugar in the body
Fruit juices
topic Càncer
Sucre en l'organisme
Sucs de fruita
Cancer
Sugar in the body
Fruit juices
description The consumption of sweet beverages, including sugar-sweetened beverages (SSB), artificial-sweetened beverages (ASB) and fruit juices (FJ), is associated with the risk of different cardiometabolic diseases. It may also be linked to the development of certain types of tumors. We carried out a systematic review and meta-analysis of observational studies aimed at examining the association between sweet beverage intake and cancer risk. Suitable articles published up to June 2020 were sourced through PubMed, Web of Science and SCOPUS databases. Overall, 64 studies were identified, of which 27 were selected for the meta-analysis. This was performed by analyzing the multivariable-adjusted OR, RR or HR of the highest sweet beverage intake categories compared to the lowest one. Random effects showed significant positive association between SSB intake and breast (RR: 1.14, 95% CI: 1.01-1.30) and prostate cancer risk (RR: 1.18, 95% CI: 1.10-1.27) and also between FJs and prostate cancer risk (RR: 1.03, 95% CI: 1.01-1.05). Although the statistically significant threshold was not reached, there tended to be positive associations for the following: SSBs and colorectal and pancreatic cancer risk; FJs and breast, colorectal and pancreatic cancer risk; and ASBs and pancreatic cancer risk. This study recommends limiting sweet beverage consumption. Furthermore, we propose to establish a homogeneous classification of beverages and investigate them separately, to better understand their role in carcinogenesis.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/175990
url https://hdl.handle.net/2445/175990
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/nu13020516
Nutrients, 2021, vol. 13, num. 2
https://doi.org/10.3390/nu13020516
dc.rights.none.fl_str_mv cc by (c) Llaha et al., 2021
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Llaha et al., 2021
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869411774596382720
score 15,300724

Similares en LA Referencia