Molecular and Brain Volume Changes Following Aerobic Exercise, Cognitive and Combined Training in Physically Inactive Healthy Late-Middle-Aged Adults

Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week (5 days per week-45 min per day) multi-domain, single-blind, proof-of-concept randomi...

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Detalles Bibliográficos
Autores: Castells-Sánchez, Alba|||0000-0001-6075-0303, Roig-Coll, Francesca, Dacosta Aguayo, Rosalia|||0000-0003-1861-365X, Lamonja-Vicente, Noemí|||0000-0003-1342-1130, Torán-Monserrat, Pere|||0000-0002-9865-7427, Pera, Guillem|||0000-0003-3188-7268, García-Molina, Alberto|||0000-0002-5014-7591, Tormos, Jose M.|||0000-0002-8764-2289, Montero-Alía, Pilar|||0000-0002-9823-1485, Heras, Antonio|||0000-0001-8132-6712, Soriano-Raya, Juan José|||0000-0003-1902-8583, Cáceres, Cynthia|||0000-0001-6250-8529, Domenech, Sira|||0000-0002-5700-768X, Via, Marc|||0000-0002-9966-9921, Erickson, Kirk I.|||0000-0001-8736-981X, Mataró, Maria|||0000-0002-9946-2656
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:293110
Acceso en línea:https://ddd.uab.cat/record/293110
https://dx.doi.org/urn:doi:10.3389/fnhum.2022.854175
Access Level:acceso abierto
Palabra clave:Aerobic exercise
BDNF
Brain volume
Combined training
Computerized cognitive training
Neuroinflammation
Descripción
Sumario:Behavioral interventions have shown promising neuroprotective effects, but the cascade of molecular, brain and behavioral changes involved in these benefits remains poorly understood. Projecte Moviment is a 12-week (5 days per week-45 min per day) multi-domain, single-blind, proof-of-concept randomized controlled trial examining the cognitive effect and underlying mechanisms of an aerobic exercise (AE), computerized cognitive training (CCT) and a combined (COMB) groups compared to a waitlist control group. Adherence was.

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