Advances in Exosomes-Based Drug Delivery Systems.
Exosomes, a subgroup of extracellular vesicles, are important mediators of long-distance intercellular communication and are involved in a diverse range of biological processes such as the transport of lipids, proteins, and nucleic acids. Researchers, seeing the problems caused by the toxic effects...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de Salamanca (USAL) |
| Repositorio: | GREDOS. Repositorio Institucional de la Universidad de Salamanca |
| OAI Identifier: | oai:gredos.usal.es:10366/162258 |
| Acceso en línea: | https://onlinelibrary.wiley.com/doi/10.1002/mabi.202000269 http://hdl.handle.net/10366/162258 |
| Access Level: | acceso abierto |
| Palabra clave: | cancer therapy drug delivery exosomes mesenchymal stem cells neurological diseases Exosomes Mesenchymal Stromal Cells Drug Delivery Systems exosomas sistemas de liberación de medicamentos células del estroma mesenquimatoso |
| Sumario: | Exosomes, a subgroup of extracellular vesicles, are important mediators of long-distance intercellular communication and are involved in a diverse range of biological processes such as the transport of lipids, proteins, and nucleic acids. Researchers, seeing the problems caused by the toxic effects and clearance of synthetic nanoparticles, consider exosomes as an interesting alternative to such nanoparticles in the specific and controlled transport of drugs. In recent years, there have been remarkable advances in the use of exosomes in cancer therapeutics or for treating neurological diseases, among other applications. The objective of this work is to analyze studies focused on exosomes used in drug delivery system, present and future applications in this field of research are discussed based on the results obtained. |
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