Tissue distribution of retinoids in common dolphins (Delphinus delphis).

Exposure to organochlorines induces retinoid deficiency in mammals; hence, retinoids are potential biomarkers of the impact of these pollutants. Appropriate target tissues to monitor retinoids in cetaceans have not been properly identified because of a lack of information on the contribution of each...

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Autores: Tornero Álvarez, Ma. Victoria, Borrell Thió, Assumpció, Forcada i Nogués, Jaume, Aguilar, Àlex
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/58412
Acesso em linha:https://hdl.handle.net/2445/58412
Access Level:acceso abierto
Palavra-chave:Toxicologia ambiental
Dofins
Retinoides
Marcadors bioquímics
Environmental toxicology
Dolphins
Retinoids
Biochemical markers
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spelling Tissue distribution of retinoids in common dolphins (Delphinus delphis).Tornero Álvarez, Ma. VictoriaBorrell Thió, AssumpcióForcada i Nogués, JaumeAguilar, ÀlexToxicologia ambientalDofinsRetinoidesMarcadors bioquímicsEnvironmental toxicologyDolphinsRetinoidsBiochemical markersExposure to organochlorines induces retinoid deficiency in mammals; hence, retinoids are potential biomarkers of the impact of these pollutants. Appropriate target tissues to monitor retinoids in cetaceans have not been properly identified because of a lack of information on the contribution of each tissue to total body retinoids. Therefore, we have addressed this issue by studying the contribution of the main body tissues to retinoids in 21 common dolphins obtained from incidental catches and in apparent good health and nutritive condition. Although concentrations in the liver were highest, those in blubber were also high and accounted for 43% of the total retinoid load of the compartments examined. As blubber can be obtained using non-invasive biopsy techniques, this tissue is proposed as a reliable indicator of retinoid status in cetaceans. However, blubber topographical variation in structure and composition requires standardization of sampling sites. Retinoid concentrations did not differ significantly between sexes or with body size for any of the tissues, but the lipid content of blubber strongly influenced these concentrations. Biopsies from healthy, free-ranging individuals are preferred to samples from stranded animals. Further research on the influence of factors (age, sex, reproductive condition, diet) that potentially affect retinoid levels is required to implement the use of retinoids as biomarkers of pollutant exposure in cetaceans.Inter-Research2004info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/58412Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: http://www.int-res.com/abstracts/meps/v280/p275-283/Marine Ecology Progress Series, 2004, vol. 280, p. 275-283(c) Inter-Research, 2004info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/584122026-05-27T06:46:51Z
dc.title.none.fl_str_mv Tissue distribution of retinoids in common dolphins (Delphinus delphis).
title Tissue distribution of retinoids in common dolphins (Delphinus delphis).
spellingShingle Tissue distribution of retinoids in common dolphins (Delphinus delphis).
Tornero Álvarez, Ma. Victoria
Toxicologia ambiental
Dofins
Retinoides
Marcadors bioquímics
Environmental toxicology
Dolphins
Retinoids
Biochemical markers
title_short Tissue distribution of retinoids in common dolphins (Delphinus delphis).
title_full Tissue distribution of retinoids in common dolphins (Delphinus delphis).
title_fullStr Tissue distribution of retinoids in common dolphins (Delphinus delphis).
title_full_unstemmed Tissue distribution of retinoids in common dolphins (Delphinus delphis).
title_sort Tissue distribution of retinoids in common dolphins (Delphinus delphis).
dc.creator.none.fl_str_mv Tornero Álvarez, Ma. Victoria
Borrell Thió, Assumpció
Forcada i Nogués, Jaume
Aguilar, Àlex
author Tornero Álvarez, Ma. Victoria
author_facet Tornero Álvarez, Ma. Victoria
Borrell Thió, Assumpció
Forcada i Nogués, Jaume
Aguilar, Àlex
author_role author
author2 Borrell Thió, Assumpció
Forcada i Nogués, Jaume
Aguilar, Àlex
author2_role author
author
author
dc.subject.none.fl_str_mv Toxicologia ambiental
Dofins
Retinoides
Marcadors bioquímics
Environmental toxicology
Dolphins
Retinoids
Biochemical markers
topic Toxicologia ambiental
Dofins
Retinoides
Marcadors bioquímics
Environmental toxicology
Dolphins
Retinoids
Biochemical markers
description Exposure to organochlorines induces retinoid deficiency in mammals; hence, retinoids are potential biomarkers of the impact of these pollutants. Appropriate target tissues to monitor retinoids in cetaceans have not been properly identified because of a lack of information on the contribution of each tissue to total body retinoids. Therefore, we have addressed this issue by studying the contribution of the main body tissues to retinoids in 21 common dolphins obtained from incidental catches and in apparent good health and nutritive condition. Although concentrations in the liver were highest, those in blubber were also high and accounted for 43% of the total retinoid load of the compartments examined. As blubber can be obtained using non-invasive biopsy techniques, this tissue is proposed as a reliable indicator of retinoid status in cetaceans. However, blubber topographical variation in structure and composition requires standardization of sampling sites. Retinoid concentrations did not differ significantly between sexes or with body size for any of the tissues, but the lipid content of blubber strongly influenced these concentrations. Biopsies from healthy, free-ranging individuals are preferred to samples from stranded animals. Further research on the influence of factors (age, sex, reproductive condition, diet) that potentially affect retinoid levels is required to implement the use of retinoids as biomarkers of pollutant exposure in cetaceans.
publishDate 2004
dc.date.none.fl_str_mv 2004
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/58412
url https://hdl.handle.net/2445/58412
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://www.int-res.com/abstracts/meps/v280/p275-283/
Marine Ecology Progress Series, 2004, vol. 280, p. 275-283
dc.rights.none.fl_str_mv (c) Inter-Research, 2004
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Inter-Research, 2004
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Inter-Research
publisher.none.fl_str_mv Inter-Research
dc.source.none.fl_str_mv Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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