Multiscale modeling for complex chemical systems: highlights about the Nobel Prize in Chemistry 2013

The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel for the development of multiscale models for complex chemical systems. From the simplest approximation of molecular mechanics (MM) to quantum mechanics (QM), computational techniques allow simul...

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Detalles Bibliográficos
Autores: Estrada-Tejedor, Roger, Ros-Blanco, Laia, Teixidó, Jordi
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Universitat Ramon Llull (URL)
Repositorio:DAU Arxiu Digital de la Universitat Ramon Llull
OAI Identifier:oai:dau.url.edu:20.500.14342/1146
Acceso en línea:http://hdl.handle.net/20.500.14342/1146
Access Level:acceso abierto
Palabra clave:Quàntums, Teoria dels
Premis Nobel
Karplus, Martin, 1930-
Levitt, Michael, 1947-
Warshel, Arieh
QM/MM
Quantum mechanics
Molecular mechanics
Nobel Prize
Molecular Modeling
Mecánica cuántica
Mecánica molecular
Premio Nobel
Modelización molecular
Mecànica quàntica
Mecànica molecular
Premi Nobel
Modelització molecular
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Descripción
Sumario:The Nobel Prize in Chemistry 2013 was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel for the development of multiscale models for complex chemical systems. From the simplest approximation of molecular mechanics (MM) to quantum mechanics (QM), computational techniques allow simulating a great variety of chemical systems. Combined QM/MM methodologies, however, are the best consensus for treating complex biological systems. Herein we review the theoretical basis of QM/MM methods and their applications during the last twenty years.