A new labdane diterpene and other constituents from Marrubium deserti Noe ex Coss

The phytochemical study of the chloroform soluble part of the hydroalcoholic extract of Marrubium deserti allowed us to describe a new labdane diterpene, 6-dehydroxy-19-acetyl marrubenol (3) beside three other diterpenes: 19-acetyl-marrubenol (6), 6-acetyl-marrubenol (7) and 16-epoxy-9-hydroxylabda-...

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Detalles Bibliográficos
Autores: Dendougui, Hocine, Seghir, Souad, Belloum, Zahia, Benayache, Fadila, León, Francisco, Brouard, Ignacio, Bermejo, Jaime, Benayache, Samir
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/199650
Acceso en línea:http://hdl.handle.net/10261/199650
Access Level:acceso abierto
Palabra clave:Lamiaceae
Marrubium deserti
Diterpenoids
Sterols
Phytol
Descripción
Sumario:The phytochemical study of the chloroform soluble part of the hydroalcoholic extract of Marrubium deserti allowed us to describe a new labdane diterpene, 6-dehydroxy-19-acetyl marrubenol (3) beside three other diterpenes: 19-acetyl-marrubenol (6), 6-acetyl-marrubenol (7) and 16-epoxy-9-hydroxylabda-13(16), 14- diene (1). This latter derivative is described for the first time as natural compound. Phytol (2), and three sterols: β-sitosterol (4), stigmasterol (5) and β-sitosterol 3-O-glucoside (8) were also isolated from this species. Structure elucidation of the isolated compounds was accomplished by means of spectroscopic techniques, especially NMR spectroscopy and mass spectrometry.