p75NTR in Huntington's disease: beyond the basal ganglia

Huntington’s disease (HD) is a fatal neurodegenerative disorder with a characteristic phenotype including chorea and dystonia, uncoordinated fine movements, cognitive decline and psychiatric disturbances. Even though the clinical diagnosis of HD relies on the manifestation of motor abnormalities, th...

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Detalles Bibliográficos
Autores: Brito, Verónica, Ginés Padrós, Silvia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/119016
Acceso en línea:https://hdl.handle.net/2445/119016
Access Level:acceso abierto
Palabra clave:Corea de Huntington
Malalties neurodegeneratives
Ganglis basals
Hipocamp (Cervell)
Huntington's chorea
Neurodegenerative Diseases
Basal ganglia
Hippocampus (Brain)
Descripción
Sumario:Huntington’s disease (HD) is a fatal neurodegenerative disorder with a characteristic phenotype including chorea and dystonia, uncoordinated fine movements, cognitive decline and psychiatric disturbances. Even though the clinical diagnosis of HD relies on the manifestation of motor abnormalities, the associated memory impairments have been growing in prominence. Indeed, cognitive deficits are evident along all the disease process even in the prodrome before any motor diagnosis is given.