Wine, alcohol, polyphenols and cardiovascular disease

Abstract. Excessive alcohol consumption is associated with increased morbidity and mortality as well as with labour and traffic accidents. However, current evidence suggests beneficial effects of moderate drinking on cardiovascular events including coronary heart disease, ischaemic stroke, periphera...

Full description

Bibliographic Details
Authors: Estruch Riba, Ramon, Lamuela Raventós, Rosa Ma.
Format: article
Status:Published version
Publication Date:2014
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/61724
Online Access:https://hdl.handle.net/2445/61724
Access Level:Open access
Keyword:Vi
Polifenols
Malalties cardiovasculars
Consum d'alcohol
Estrès oxidatiu
Inflamació
Wine
Polyphenols
Cardiovascular diseases
Drinking of alcoholic beverages
Oxidative stress
Inflammation
id ES_7d3acce16a1ea09a1bd6cb66f65aaa1d
oai_identifier_str oai:recercat.cat:2445/61724
network_acronym_str ES
network_name_str España
repository_id_str
spelling Wine, alcohol, polyphenols and cardiovascular diseaseEstruch Riba, RamonLamuela Raventós, Rosa Ma.ViPolifenolsMalalties cardiovascularsConsum d'alcoholEstrès oxidatiuInflamacióWinePolyphenolsCardiovascular diseasesDrinking of alcoholic beveragesOxidative stressInflammationAbstract. Excessive alcohol consumption is associated with increased morbidity and mortality as well as with labour and traffic accidents. However, current evidence suggests beneficial effects of moderate drinking on cardiovascular events including coronary heart disease, ischaemic stroke, peripheral arterial disease and congestive heart failure. The underlying mechanisms to explain these protective effects against coronary heart disease include an increase in high-density lipoprotein cholesterol and an increase in insulin sensitivity, and a decrease in platelet aggregation and circulating concentrations of fibrinogen. However, there are discrepancies regarding the specific effects of different types of beverages on the cardiovascular system, and also whether the possible protective effects of alcoholic beverages are due to their alcohol component (ethanol) or non-alcoholic products containing, mainly polyphenols. Recent randomised clinical trials have shown that wine, a polyphenol-rich alcoholic beverage, provides higher antioxidant and anti-inflammatory effects than some spirits such as gin, a polyphenol-free alcoholic beverage. In addition, dealcoholized red wine decreases blood pressure through a nitric oxide mediated mechanism, suggesting a protective effect of polyphenols on vascular function. Other studies performed in women have observed that daily doses of 15<br>20 g of alcohol as red wine are sufficient to elicit protective effects similar to those observed in men who consumed higher doses of wine. In conclusion, moderate consumption of wine exerts a protective effect on biomarkers related to the progression and development of atherosclerosis due to its alcoholic (ethanol) and non-alcoholic (polyphenols) content. Women are more sensitive to the beneficial effects of wine.IOS Press2015201520142015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9 p.application/pdfhttps://hdl.handle.net/2445/61724Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: http://dx.doi.org/10.3233/NUA-140039Nutrition and Aging, 2014, vol. 2, num. 2-3, p. 101-109http://dx.doi.org/10.3233/NUA-140039(c) Estruch Riba, Ramon et al., 2014info:eu-repo/semantics/openAccessoai:recercat.cat:2445/617242026-05-29T05:05:01Z
dc.title.none.fl_str_mv Wine, alcohol, polyphenols and cardiovascular disease
title Wine, alcohol, polyphenols and cardiovascular disease
spellingShingle Wine, alcohol, polyphenols and cardiovascular disease
Estruch Riba, Ramon
Vi
Polifenols
Malalties cardiovasculars
Consum d'alcohol
Estrès oxidatiu
Inflamació
Wine
Polyphenols
Cardiovascular diseases
Drinking of alcoholic beverages
Oxidative stress
Inflammation
title_short Wine, alcohol, polyphenols and cardiovascular disease
title_full Wine, alcohol, polyphenols and cardiovascular disease
title_fullStr Wine, alcohol, polyphenols and cardiovascular disease
title_full_unstemmed Wine, alcohol, polyphenols and cardiovascular disease
title_sort Wine, alcohol, polyphenols and cardiovascular disease
dc.creator.none.fl_str_mv Estruch Riba, Ramon
Lamuela Raventós, Rosa Ma.
author Estruch Riba, Ramon
author_facet Estruch Riba, Ramon
Lamuela Raventós, Rosa Ma.
author_role author
author2 Lamuela Raventós, Rosa Ma.
author2_role author
dc.subject.none.fl_str_mv Vi
Polifenols
Malalties cardiovasculars
Consum d'alcohol
Estrès oxidatiu
Inflamació
Wine
Polyphenols
Cardiovascular diseases
Drinking of alcoholic beverages
Oxidative stress
Inflammation
topic Vi
Polifenols
Malalties cardiovasculars
Consum d'alcohol
Estrès oxidatiu
Inflamació
Wine
Polyphenols
Cardiovascular diseases
Drinking of alcoholic beverages
Oxidative stress
Inflammation
description Abstract. Excessive alcohol consumption is associated with increased morbidity and mortality as well as with labour and traffic accidents. However, current evidence suggests beneficial effects of moderate drinking on cardiovascular events including coronary heart disease, ischaemic stroke, peripheral arterial disease and congestive heart failure. The underlying mechanisms to explain these protective effects against coronary heart disease include an increase in high-density lipoprotein cholesterol and an increase in insulin sensitivity, and a decrease in platelet aggregation and circulating concentrations of fibrinogen. However, there are discrepancies regarding the specific effects of different types of beverages on the cardiovascular system, and also whether the possible protective effects of alcoholic beverages are due to their alcohol component (ethanol) or non-alcoholic products containing, mainly polyphenols. Recent randomised clinical trials have shown that wine, a polyphenol-rich alcoholic beverage, provides higher antioxidant and anti-inflammatory effects than some spirits such as gin, a polyphenol-free alcoholic beverage. In addition, dealcoholized red wine decreases blood pressure through a nitric oxide mediated mechanism, suggesting a protective effect of polyphenols on vascular function. Other studies performed in women have observed that daily doses of 15<br>20 g of alcohol as red wine are sufficient to elicit protective effects similar to those observed in men who consumed higher doses of wine. In conclusion, moderate consumption of wine exerts a protective effect on biomarkers related to the progression and development of atherosclerosis due to its alcoholic (ethanol) and non-alcoholic (polyphenols) content. Women are more sensitive to the beneficial effects of wine.
publishDate 2014
dc.date.none.fl_str_mv 2014
2015
2015
2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/61724
url https://hdl.handle.net/2445/61724
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.3233/NUA-140039
Nutrition and Aging, 2014, vol. 2, num. 2-3, p. 101-109
http://dx.doi.org/10.3233/NUA-140039
dc.rights.none.fl_str_mv (c) Estruch Riba, Ramon et al., 2014
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Estruch Riba, Ramon et al., 2014
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9 p.
application/pdf
dc.publisher.none.fl_str_mv IOS Press
publisher.none.fl_str_mv IOS Press
dc.source.none.fl_str_mv Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869411648332103680
score 15,81155

Similar Items