Starch-silver hybrid nanoparticles: A novel antimicrobial agent

Starch-silver hybrid nanoparticles were synthesized by a method combining nanoprecipitation and autoclaving. Starch nanoparticles (SNPs) were used as matrix and stabilising agent for the silver nanoparticles (AgNPs) by using native starches from different botanical sources. The hybrid Ag-SNPs were c...

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Detalles Bibliográficos
Autores: Morán, Diana, López-Carballo, Gracia, Gavara, Rafael, Gutiérrez, Gemma, Matos, María
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/389183
Acceso en línea:http://hdl.handle.net/10261/389183
https://api.elsevier.com/content/abstract/scopus_id/105002054749
Access Level:acceso abierto
Palabra clave:Antimicrobial
Hybrid nanoparticles
Nanocarriers
Silver nanoparticles
Starch nanoparticles
silver
nanoparticles
starch
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spelling Starch-silver hybrid nanoparticles: A novel antimicrobial agentMorán, DianaLópez-Carballo, GraciaGavara, RafaelGutiérrez, GemmaMatos, MaríaAntimicrobialHybrid nanoparticlesNanocarriersSilver nanoparticlesStarch nanoparticlessilvernanoparticlesstarchStarch-silver hybrid nanoparticles were synthesized by a method combining nanoprecipitation and autoclaving. Starch nanoparticles (SNPs) were used as matrix and stabilising agent for the silver nanoparticles (AgNPs) by using native starches from different botanical sources. The hybrid Ag-SNPs were characterized in terms of size, charge, morphology and molecular structure. Quantitative analysis of Ag was also carried out. Spherical SNPs were obtained with all starches with sizes ranging from 82 to 90 nm and neutral charge (zeta potentials around −1 mV). HR-TEM micrographs demonstrated the presence of AgNPs of 5–10 nm. FTIR showed AgNPs encapsulation within the SNPs. The antimicrobial activity of the formulations was demonstrated against Escherichia coli and Staphylococcus aureus both in solid medium by the diffusion method and in microdilution method. Slightly higher antibacterial activity against E. coli was observed. Hybrid amaranth Ag-SNPs with 0.0005 M and 0.001 M of AgNO3 showed log reductions of 4.21 and 4.35 respectively for S. aureus and bactericide effect against E.coli. Therefore, these hybrid NPs can be considered as sustainable promising nanomaterial with antimicrobial activity.This work was supported by the Ministerio de Economía y Competitividad (MINECO, Spain), under Grant PID2020–119087RB-I00 and was also co-financed by Consejería de Educación y Ciencia del Principado de Asturias (AYUD/2021/52132).With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2021-001189-S)Peer reviewedElsevierMinisterio de Ciencia, Innovación y Universidades (España)Agencia Estatal de Investigación (España)Principado de AsturiasMinisterio de Ciencia e Innovación (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202520252025info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/389183https://api.elsevier.com/content/abstract/scopus_id/105002054749reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-119087RB-I00info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/CEX2021-001189-SColloids and Surfaces A: Physicochemical and Engineering Aspectshttps://doi.org/10.1016/j.colsurfa.2025.136797Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3891832026-05-22T06:33:51Z
dc.title.none.fl_str_mv Starch-silver hybrid nanoparticles: A novel antimicrobial agent
title Starch-silver hybrid nanoparticles: A novel antimicrobial agent
spellingShingle Starch-silver hybrid nanoparticles: A novel antimicrobial agent
Morán, Diana
Antimicrobial
Hybrid nanoparticles
Nanocarriers
Silver nanoparticles
Starch nanoparticles
silver
nanoparticles
starch
title_short Starch-silver hybrid nanoparticles: A novel antimicrobial agent
title_full Starch-silver hybrid nanoparticles: A novel antimicrobial agent
title_fullStr Starch-silver hybrid nanoparticles: A novel antimicrobial agent
title_full_unstemmed Starch-silver hybrid nanoparticles: A novel antimicrobial agent
title_sort Starch-silver hybrid nanoparticles: A novel antimicrobial agent
dc.creator.none.fl_str_mv Morán, Diana
López-Carballo, Gracia
Gavara, Rafael
Gutiérrez, Gemma
Matos, María
author Morán, Diana
author_facet Morán, Diana
López-Carballo, Gracia
Gavara, Rafael
Gutiérrez, Gemma
Matos, María
author_role author
author2 López-Carballo, Gracia
Gavara, Rafael
Gutiérrez, Gemma
Matos, María
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Ministerio de Ciencia, Innovación y Universidades (España)
Agencia Estatal de Investigación (España)
Principado de Asturias
Ministerio de Ciencia e Innovación (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Antimicrobial
Hybrid nanoparticles
Nanocarriers
Silver nanoparticles
Starch nanoparticles
silver
nanoparticles
starch
topic Antimicrobial
Hybrid nanoparticles
Nanocarriers
Silver nanoparticles
Starch nanoparticles
silver
nanoparticles
starch
description Starch-silver hybrid nanoparticles were synthesized by a method combining nanoprecipitation and autoclaving. Starch nanoparticles (SNPs) were used as matrix and stabilising agent for the silver nanoparticles (AgNPs) by using native starches from different botanical sources. The hybrid Ag-SNPs were characterized in terms of size, charge, morphology and molecular structure. Quantitative analysis of Ag was also carried out. Spherical SNPs were obtained with all starches with sizes ranging from 82 to 90 nm and neutral charge (zeta potentials around −1 mV). HR-TEM micrographs demonstrated the presence of AgNPs of 5–10 nm. FTIR showed AgNPs encapsulation within the SNPs. The antimicrobial activity of the formulations was demonstrated against Escherichia coli and Staphylococcus aureus both in solid medium by the diffusion method and in microdilution method. Slightly higher antibacterial activity against E. coli was observed. Hybrid amaranth Ag-SNPs with 0.0005 M and 0.001 M of AgNO3 showed log reductions of 4.21 and 4.35 respectively for S. aureus and bactericide effect against E.coli. Therefore, these hybrid NPs can be considered as sustainable promising nanomaterial with antimicrobial activity.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/389183
https://api.elsevier.com/content/abstract/scopus_id/105002054749
url http://hdl.handle.net/10261/389183
https://api.elsevier.com/content/abstract/scopus_id/105002054749
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-119087RB-I00
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/CEX2021-001189-S
Colloids and Surfaces A: Physicochemical and Engineering Aspects
https://doi.org/10.1016/j.colsurfa.2025.136797
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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