Proposing a Parkinson's disease-specific tremor scale from the MDS-UPDRS

Background: This article proposes an International Parkinson and Movement Disorder Society (MDS)-UPDRS tremor-based scale and describes its measurement properties, with a view to developing an improved scale for assessing tremor in Parkinson's disease (PD). Methods: This was a cross-sectional,...

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Detalles Bibliográficos
Autores: Forjaz, Maria João, Ayala, Alba, Testa, Claudia M, Bain, Peter G, Elble, Rodger, Haubenberger, Dietrich, Rodriguez-Blazquez, Carmen, Deuschl, Günther, Martínez-Martín, Pablo
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/8096
Acceso en línea:http://hdl.handle.net/20.500.12105/8096
Access Level:acceso abierto
Palabra clave:Aged
Cross-Sectional Studies
Female
Humans
Male
Middle Aged
Parkinson Disease
Psychometrics
Reproducibility of Results
Tremor
Severity of Illness Index
Descripción
Sumario:Background: This article proposes an International Parkinson and Movement Disorder Society (MDS)-UPDRS tremor-based scale and describes its measurement properties, with a view to developing an improved scale for assessing tremor in Parkinson's disease (PD). Methods: This was a cross-sectional, multicenter study of 435 PD patients. Rasch analysis was performed on the 11 MDS-UPDRS tremor items. Construct validity, precision, and test-retest reliability were also analyzed. Results: After some modifications, which included removal of an item owing to redundancy, the obtained MDS-UPDRS tremor scale showed moderate reliability, unidimensionality, absence of differential item functioning, satisfactory convergent validity with medication, and better precision than the raw sum score. However, the scale displayed a floor effect and a need for more items measuring lower levels of tremor. Conclusions: The MDS-UPDRS tremor scale provides linear scores that can be used to assess tremor in PD in a valid, reliable way. The scale might benefit from modifications and studies that analyze its responsiveness.