SEOM clinical guidelines for the treatment of malignant pleural mesothelioma (2020)

Mesothelioma is a rare and aggressive tumour with dismal prognosis arising in the pleura and associated with asbestos exposure. Its incidence is on the rise worldwide. In selected patients with early-stage MPM, a maximal surgical cytoreduction in combination with additional antitumour treatment may...

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Detalhes bibliográficos
Autores: Nadal, E., Bosch-Barrera, Joaquim, Cedrés, Susana, Coves Sarto, Juan, Garcia-Campelo, R., Guirado, M., Lopez-Castro, R., Ortega, A. L., Vicente, D., de Castro-Carpeno, J.
Formato: artículo
Fecha de publicación:2021
País:España
Recursos:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/16111
Acesso em linha:https://hdl.handle.net/20.500.13003/16111
Access Level:acceso abierto
Palavra-chave:Malignant pleural mesothelioma
Clinical guidelines
Treatment
Diagnostic
Descrição
Resumo:Mesothelioma is a rare and aggressive tumour with dismal prognosis arising in the pleura and associated with asbestos exposure. Its incidence is on the rise worldwide. In selected patients with early-stage MPM, a maximal surgical cytoreduction in combination with additional antitumour treatment may be considered in selected patients assessed by a multidisciplinary tumor board. In patients with unresectable or advanced MPM, chemotherapy with platinum plus pemetrexed is the standard of care. Currently, no standard salvage therapy has been approved yet, but second-line chemotherapy with vinorelbine or gemcitabine is commonly used. Novel therapeutic approaches based on dual immunotherapy or chemotherapy plus immunotherapy demonstrated promising survival benefit and will probably be incorporated in the future.