Concentrations of per- and polyfluoroalkyl substances (PFAS) in paired tap water and blood samples during pregnancy
Per- and polyfluoroalkyl substances (PFAS) are water-soluble chemicals of concern due to their persistence, ubiquity, and toxicity. We explored correlations between drinking water and blood PFAS levels in a subset of the mother-child Barcelona Life Study Cohort (BiSC), Barcelona, Spain (2021). For 1...
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2024 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/351448 |
| Acceso en línea: | http://hdl.handle.net/10261/351448 https://api.elsevier.com/content/abstract/scopus_id/85172095247 |
| Access Level: | acceso abierto |
| Palabra clave: | PFAS Biomonitoring Drinking water Exposure assessment http://metadata.un.org/sdg/3 Ensure healthy lives and promote well-being for all at all ages |
| Sumario: | Per- and polyfluoroalkyl substances (PFAS) are water-soluble chemicals of concern due to their persistence, ubiquity, and toxicity. We explored correlations between drinking water and blood PFAS levels in a subset of the mother-child Barcelona Life Study Cohort (BiSC), Barcelona, Spain (2021). For 105 study participants, we analyzed 35 PFAS in tap water (unfiltered and filtered) and 23 PFAS in 98 paired plasma samples during the 3rd trimester, using LC-MS/MS. Water consumption habits were ascertained at the third trimester through questionnaires. The majority of participants consumed bottled water (56.2%), 5/35 PFAS were detected in unfiltered tap water, 4/35 PFAS in activated carbon filtered tap water samples, and 14/23 PFAS in plasma samples. Our results showed that PFHpA at the observed concentrations in drinking water was significantly correlated with paired plasma levels (R = 0.2; p = 0.04). |
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