Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies

The introduction of hybrid materials in regenerative medicine has solved some problems related to the mechanical and bioactive properties of biomaterials. Calcium phosphates and their derivatives have provided the basis for inorganic components, thanks to their good bioactivity, especially in bone r...

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Detalles Bibliográficos
Autores: Sachot, Nadège, Engel, Elisabeth, Castaño Linares, Óscar
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2014
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/118748
Acceso en línea:https://hdl.handle.net/2445/118748
Access Level:acceso abierto
Palabra clave:Polímers en medicina
Nanopartícules
Interacció cel·lular
Enginyeria de teixits
Polymers in medicine
Nanoparticles
Cell interaction
Tissue engineering
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spelling Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative TherapiesSachot, NadègeEngel, ElisabethCastaño Linares, ÓscarPolímers en medicinaNanopartículesInteracció cel·lularEnginyeria de teixitsPolymers in medicineNanoparticlesCell interactionTissue engineeringThe introduction of hybrid materials in regenerative medicine has solved some problems related to the mechanical and bioactive properties of biomaterials. Calcium phosphates and their derivatives have provided the basis for inorganic components, thanks to their good bioactivity, especially in bone regeneration. When mixed with biodegradable polymers, the result is a synergic association that mimics the composition of many tissues of the human body and, additionally, exhibits suitable mechanical properties. Together with the development of nanotechnology and new synthesis methods, hybrids offer a promising option for the development of a third or fourth generation of smart biomaterials and scaffolds to guide the regeneration of natural tissues, with an optimum efficiency/cost ratio. Their potential bioactivity, as well as other valuable features of hybrids, open promising new pathways for their use in bone regeneration and other tissue repair therapies. This review provides a comprehensive overview of the different hybrid organic-inorganic scaffolding biomaterials developed so far for regenerative therapies, especially in bone. It also looks at the potential for research into hybrid materials for other, softer tissues, which is still at an initial stage, but with very promising results.Bentham Science Publishers2017201720142017info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion16 p.application/pdfhttps://hdl.handle.net/2445/118748Articles publicats en revistes (Enginyeria Electrònica i Biomèdica)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.2174/1385272819666140806200355Current Organic Chemistry, 2014, vol. 18, num. 18, p. 2299-2314https://doi.org/10.2174/1385272819666140806200355(c) Bentham Science Publishers, 2014info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1187482026-05-29T05:05:01Z
dc.title.none.fl_str_mv Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
title Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
spellingShingle Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
Sachot, Nadège
Polímers en medicina
Nanopartícules
Interacció cel·lular
Enginyeria de teixits
Polymers in medicine
Nanoparticles
Cell interaction
Tissue engineering
title_short Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
title_full Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
title_fullStr Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
title_full_unstemmed Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
title_sort Hybrid organic-inorganic Scaffolding Biomaterials for Regenerative Therapies
dc.creator.none.fl_str_mv Sachot, Nadège
Engel, Elisabeth
Castaño Linares, Óscar
author Sachot, Nadège
author_facet Sachot, Nadège
Engel, Elisabeth
Castaño Linares, Óscar
author_role author
author2 Engel, Elisabeth
Castaño Linares, Óscar
author2_role author
author
dc.subject.none.fl_str_mv Polímers en medicina
Nanopartícules
Interacció cel·lular
Enginyeria de teixits
Polymers in medicine
Nanoparticles
Cell interaction
Tissue engineering
topic Polímers en medicina
Nanopartícules
Interacció cel·lular
Enginyeria de teixits
Polymers in medicine
Nanoparticles
Cell interaction
Tissue engineering
description The introduction of hybrid materials in regenerative medicine has solved some problems related to the mechanical and bioactive properties of biomaterials. Calcium phosphates and their derivatives have provided the basis for inorganic components, thanks to their good bioactivity, especially in bone regeneration. When mixed with biodegradable polymers, the result is a synergic association that mimics the composition of many tissues of the human body and, additionally, exhibits suitable mechanical properties. Together with the development of nanotechnology and new synthesis methods, hybrids offer a promising option for the development of a third or fourth generation of smart biomaterials and scaffolds to guide the regeneration of natural tissues, with an optimum efficiency/cost ratio. Their potential bioactivity, as well as other valuable features of hybrids, open promising new pathways for their use in bone regeneration and other tissue repair therapies. This review provides a comprehensive overview of the different hybrid organic-inorganic scaffolding biomaterials developed so far for regenerative therapies, especially in bone. It also looks at the potential for research into hybrid materials for other, softer tissues, which is still at an initial stage, but with very promising results.
publishDate 2014
dc.date.none.fl_str_mv 2014
2017
2017
2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/118748
url https://hdl.handle.net/2445/118748
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.2174/1385272819666140806200355
Current Organic Chemistry, 2014, vol. 18, num. 18, p. 2299-2314
https://doi.org/10.2174/1385272819666140806200355
dc.rights.none.fl_str_mv (c) Bentham Science Publishers, 2014
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Bentham Science Publishers, 2014
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 16 p.
application/pdf
dc.publisher.none.fl_str_mv Bentham Science Publishers
publisher.none.fl_str_mv Bentham Science Publishers
dc.source.none.fl_str_mv Articles publicats en revistes (Enginyeria Electrònica i Biomèdica)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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