Efficacy, predictability and safety of long-term orthokeratology: an 18-year follow-up study

Purpose: To determine the efficacy, predictability and safety of long-term orthokeratology in children and adults. Methods: Case histories of 300 orthokeratology patients (596 eyes; 34.3% children; 65.7% adults) were reviewed to collect information on demographics, corneal and refractive parameters,...

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Detalles Bibliográficos
Autores: Gispets Parcerisas, Joan|||0000-0002-4671-6931, Yébana Rubio, Pilar, Lupón Bas, Núria|||0000-0002-4489-286X, Cardona Torradeflot, Genís|||0000-0002-4770-8992, Pérez Corral, Juan Enrique|||0000-0002-4370-3991, Pauné Fabré, Jaime|||0000-0002-2493-3791, Cortilla Santamaria, Bernat
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/360357
Acceso en línea:https://hdl.handle.net/2117/360357
https://dx.doi.org/10.1016/j.clae.2021.101530
Access Level:acceso abierto
Palabra clave:Contact lenses
Keratitis
Contact lens
Contact lens complications
Corneal staining
Microbial keratitis
Orthokeratology
Lents de contacte
Queratitis
Àrees temàtiques de la UPC::Ciències de la visió
Descripción
Sumario:Purpose: To determine the efficacy, predictability and safety of long-term orthokeratology in children and adults. Methods: Case histories of 300 orthokeratology patients (596 eyes; 34.3% children; 65.7% adults) were reviewed to collect information on demographics, corneal and refractive parameters, visual acuity, residual refraction and adverse effects. Predictability was defined as the percentage of eyes with absolute values of spherical equivalent refraction = 0.5 D of emmetropia, and efficacy as the ratio of post-orthokeratology uncorrected and pre-orthokeratology corrected distance visual acuity. Results: Median duration of treatment was 37 and 28.5 months in children and adults, respectively (p = 0.022). During the first year, 17.2% of children and 33% of adults ceased lens wear (p < 0.001). For children and adults with a successful ortho-k treatment of at least one year of duration, 88.7% and 95.9% of eyes had a predictable refractive outcome, and efficacy was 0.98 and 1.01, respectively. A larger percentage of children (65.7%) were free of complications than of adults (55.4%) (p = 0.015). One event of microbial keratitis occurred in adults (6.8 cases per 10,000 patient-years) and none in children. Corneal staining was the most frequent complication, with a higher incidence in adults (p = 0.007) and in higher myopia (p < 0.001), higher anterior corneal eccentricity (p = 0.019) and smaller anterior horizontal radius (p = 0.027). Conclusion: Orthokeratology is a safe and predictable long-term procedure in children and adults, with a low incidence of serious adverse effects. Corneal staining episodes are relatively frequent throughout the course of the treatment, thus highlighting the relevance of education of experienced users.