Association between Different Animal Protein Sources and Liver Status in Obese Subjects with Non-Alcoholic Fatty Liver Disease: Fatty Liver in Obesity (FLiO) Study

Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Obesity and unhealthy dietary habits are described as risk factors for NAFLD. The aim of this study was to investigate the association between the consumption of different animal protein sources...

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Detalhes bibliográficos
Autores: Recaredo, Gregorio, Marin-Alejandre, Bertha Araceli, Cantero, Irene, Monreal, J Ignacio, Herrero, Jose Ignacio, Benito-Boillos, Alberto, Elorz, Mariana, Tur, Josep A, Alfredo Martinez, J, Angeles Zulet, M, Abete, Itziar
Formato: artículo
Fecha de publicación:2019
País:España
Recursos:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/22762
Acesso em linha:https://hdl.handle.net/20.500.12105/22762
Access Level:acceso abierto
Palavra-chave:Obesity
NAFLD
Fatty liver
Red meat
Processed meat
Fish
Ferritin
Iron
Índice de Masa Corporal
Animales
Dieta Saludable
Femenino
Ferritinas
Enfermedad del Hígado Graso no Alcohólico
Carne Roja
Proteínas en la Dieta
Carne
Hígado
Masculino
Conducta Alimentaria
Manipulación de Alimentos
Peces
Factores de Riesgo
Humanos
Persona de Mediana Edad
Obesidad
Hierro
Anciano
Anciano de 80 o más Años
Composición Corporal
Adulto
Descrição
Resumo:Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Obesity and unhealthy dietary habits are described as risk factors for NAFLD. The aim of this study was to investigate the association between the consumption of different animal protein sources and hepatic status in NAFLD adults. A total of 112 overweight/obese participants with NAFLD from Fatty Liver in Obesity (FLiO) study were evaluated at baseline. Diet, body composition, and biochemical variables were evaluated. Hepatic status was also assessed by Magnetic Resonance Imaging, ultrasonography, and elastography. Red meat consumption showed a positive relationship with liver iron content (r = 0.224; p = 0.021) and ferritin concentration (r = 0.196; p = 0.037). Processed meat consumption exhibited a positive association with liver iron content (r = 0.308; p = 0.001), which was also found in the quantile regression (beta = 0.079; p = 0.028). Fish consumption was related with lower concentration of ferritin (r = -0.200; p = 0.034). This association was further evidenced in the regression model (beta = -0.720; p = 0.033). These findings suggest that the consumption of different animal protein sources differentially impact on liver status in obese subjects with NAFLD, showing fish consumption as a healthier alternative for towards NAFLD features.

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