EANM enabling guide: how to improve the accessibility of clinical dosimetry

Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry...

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Autores: Gear, Jonathan, Stokke, Caroline, Terwinghe, Christelle, Gnesin, Silvano, Sandström, Mattias, Tran-Gia, Johannes, Cremonesi, Marta, Cicone, Francesco, Verburg, Fredrik, Hustinx, Roland, Giovanella, Luca, Herrmann, Ken, Mínguez Gabiña, Pablo
Formato: artículo
Fecha de publicación:2023
País:España
Recursos:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/62581
Acesso em linha:http://hdl.handle.net/10810/62581
Access Level:acceso abierto
Palavra-chave:dosimetry
molecular radiotherapy
SPECT
nuclear medicine
quantitative imaging
optimisation
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spelling EANM enabling guide: how to improve the accessibility of clinical dosimetryGear, JonathanStokke, CarolineTerwinghe, ChristelleGnesin, SilvanoSandström, MattiasTran-Gia, JohannesCremonesi, MartaCicone, FrancescoVerburg, FredrikHustinx, RolandGiovanella, LucaHerrmann, KenMínguez Gabiña, Pablodosimetrymolecular radiotherapySPECTnuclear medicinequantitative imagingoptimisationDosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.NHS funding was provided to the NIHR Biomedical Research Centre at The Royal Marsden and the ICR.Springer202320232023info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/62581reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoIngléshttps://link.springer.com/article/10.1007/s00259-023-06226-zinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/es/© The Author(s) 2023, corrected publication 2023. This article is licensed under a Creative Commons Attri- bution 4.0 International License, which permits use, sharing, adapta- tion, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Atribución 3.0 Españaoai:addi.ehu.eus:10810/625812026-06-18T09:23:17Z
dc.title.none.fl_str_mv EANM enabling guide: how to improve the accessibility of clinical dosimetry
title EANM enabling guide: how to improve the accessibility of clinical dosimetry
spellingShingle EANM enabling guide: how to improve the accessibility of clinical dosimetry
Gear, Jonathan
dosimetry
molecular radiotherapy
SPECT
nuclear medicine
quantitative imaging
optimisation
title_short EANM enabling guide: how to improve the accessibility of clinical dosimetry
title_full EANM enabling guide: how to improve the accessibility of clinical dosimetry
title_fullStr EANM enabling guide: how to improve the accessibility of clinical dosimetry
title_full_unstemmed EANM enabling guide: how to improve the accessibility of clinical dosimetry
title_sort EANM enabling guide: how to improve the accessibility of clinical dosimetry
dc.creator.none.fl_str_mv Gear, Jonathan
Stokke, Caroline
Terwinghe, Christelle
Gnesin, Silvano
Sandström, Mattias
Tran-Gia, Johannes
Cremonesi, Marta
Cicone, Francesco
Verburg, Fredrik
Hustinx, Roland
Giovanella, Luca
Herrmann, Ken
Mínguez Gabiña, Pablo
author Gear, Jonathan
author_facet Gear, Jonathan
Stokke, Caroline
Terwinghe, Christelle
Gnesin, Silvano
Sandström, Mattias
Tran-Gia, Johannes
Cremonesi, Marta
Cicone, Francesco
Verburg, Fredrik
Hustinx, Roland
Giovanella, Luca
Herrmann, Ken
Mínguez Gabiña, Pablo
author_role author
author2 Stokke, Caroline
Terwinghe, Christelle
Gnesin, Silvano
Sandström, Mattias
Tran-Gia, Johannes
Cremonesi, Marta
Cicone, Francesco
Verburg, Fredrik
Hustinx, Roland
Giovanella, Luca
Herrmann, Ken
Mínguez Gabiña, Pablo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv dosimetry
molecular radiotherapy
SPECT
nuclear medicine
quantitative imaging
optimisation
topic dosimetry
molecular radiotherapy
SPECT
nuclear medicine
quantitative imaging
optimisation
description Dosimetry can be a useful tool for personalization of molecular radiotherapy (MRT) procedures, enabling the continuous development of theranostic concepts. However, the additional resource requirements are often seen as a barrier to implementation. This guide discusses the requirements for dosimetry and demonstrates how a dosimetry regimen can be tailored to the available facilities of a centre. The aim is to help centres wishing to initiate a dosimetry service but may not have the experience or resources of some of the more established therapy and dosimetry centres. The multidisciplinary approach and different personnel requirements are discussed and key equipment reviewed example protocols demonstrating these factors are given in the supplementary material for the main therapies carried out in nuclear medicine, including [131I]-NaI for benign thyroid disorders, [177Lu]-DOTATATE and 131I-mIBG for neuroendocrine tumours and [90Y]-microspheres for unresectable hepatic carcinoma.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/62581
url http://hdl.handle.net/10810/62581
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://link.springer.com/article/10.1007/s00259-023-06226-z
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/es/
Atribución 3.0 España
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/3.0/es/
Atribución 3.0 España
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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