Exploring the (almost) unknown: Archaeal two-component systems

Two-component systems (TCS) exist in bacteria and archaea. In contrast to the knowledge of bacterial TCSs, little information is available on their archaeal counterparts. In the current issue of Journal of Bacteriology, Galperin and coworkers present a bioinformatics analysis of TCS genes from archa...

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Detalles Bibliográficos
Autor: Krell, Tino
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/170825
Acceso en línea:http://hdl.handle.net/10261/170825
Access Level:acceso abierto
Palabra clave:Two-component regulatory systems
Archaea
Descripción
Sumario:Two-component systems (TCS) exist in bacteria and archaea. In contrast to the knowledge of bacterial TCSs, little information is available on their archaeal counterparts. In the current issue of Journal of Bacteriology, Galperin and coworkers present a bioinformatics analysis of TCS genes from archaeal genome sequences (M. Y. Galperin, K. S. Makarova, Y. I. Wolf, and E. V. Koonin, J Bacteriol 200:e00681- 17, 2018, https://doi.org/10.1128/JB.00681-17). This study identifies different aspects in which TCS-mediated signaling differs in bacteria and archaea and forms a sound basis for the experimental design of studies to increase our knowledge of this poorly investigated protein family.