Next-generation sequencing of the athletic gut microbiota: a systematic review

Aim: There is growing evidence that physical activity modulates gut microbiota composition through complex interactions between diet and microbial species. On the other hand, next-generation sequencing techniques include shotgun metagenomics and 16S amplicon sequencing. These methodologies allow a c...

Descripción completa

Detalles Bibliográficos
Autores: Sabater, Carlos, Iglesias-Gutiérrez, Eduardo, Ruíz García, Lorena, Margolles Barros, Abelardo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/351091
Acceso en línea:http://hdl.handle.net/10261/351091
https://api.elsevier.com/content/abstract/scopus_id/85181440466
Access Level:acceso abierto
Palabra clave:Gut microbiome
Athletes
Exercise
Metagenomics
Systematic review
id ES_79cd81948edf9400a7bf187228207dfc
oai_identifier_str oai:digital.csic.es:10261/351091
network_acronym_str ES
network_name_str España
repository_id_str
spelling Next-generation sequencing of the athletic gut microbiota: a systematic reviewSabater, CarlosIglesias-Gutiérrez, EduardoRuíz García, LorenaMargolles Barros, AbelardoGut microbiomeAthletesExerciseMetagenomicsSystematic reviewAim: There is growing evidence that physical activity modulates gut microbiota composition through complex interactions between diet and microbial species. On the other hand, next-generation sequencing techniques include shotgun metagenomics and 16S amplicon sequencing. These methodologies allow a comprehensive characterisation of microbial communities of athletes from different disciplines as well as non-professional players and sedentary adults exposed to training. This systematic review summarises recent applications of next-generation sequencing to characterise the athletic gut microbiome. Methods: A systematic review of microbiome research was performed to determine the association of microbiota composition profiles with sports performance. Results: Bibliographic analysis revealed the importance of a novel research trend aiming at deciphering the associations between individual microbial species and sports performance. In addition, literature review highlighted the role of butyrate-producing bacteria such as Anaerostipes hadrus, Clostridium bolteae, Faecalibacterium prausnitzii, Roseburia hominis and unidentified species belonging to Clostridiales, Lachnospiraceae and Subdoligranulum species in gut health and sports performance across several disciplines. Interestingly, metabolic activities of Prevotella copri and Veillonella atypica involved in branched amino acid and lactate metabolism may contribute to reducing muscular fatigue. Other microbial metabolic pathways of interest involved in carbohydrate metabolism showed increased proportions in athletes´ metagenomes. Conclusion: Future research will aim at developing personalised nutrition interventions to modulate key species associated with certain components of exercise.Carlos Sabater is a postdoctoral researcher supported by the Juan de la Cierva-Formación Postdoctoral Trainee Program from MICINN, the Spanish Ministry of Science and Innovation (FJC2019-042125-I).Peer reviewedOAE PublishingAgencia Estatal de Investigación (España)Ministerio de Ciencia e Innovación (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242023info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/351091https://api.elsevier.com/content/abstract/scopus_id/85181440466reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/AEI//FJC2019-042125-IThe underlying dataset has been published as supplementary material of the article in the publisher platform at https://dx.doi.org/10.20517/mrr.2022.16https://dx.doi.org/10.20517/mrr.2022.16Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3510912026-05-22T06:33:51Z
dc.title.none.fl_str_mv Next-generation sequencing of the athletic gut microbiota: a systematic review
title Next-generation sequencing of the athletic gut microbiota: a systematic review
spellingShingle Next-generation sequencing of the athletic gut microbiota: a systematic review
Sabater, Carlos
Gut microbiome
Athletes
Exercise
Metagenomics
Systematic review
title_short Next-generation sequencing of the athletic gut microbiota: a systematic review
title_full Next-generation sequencing of the athletic gut microbiota: a systematic review
title_fullStr Next-generation sequencing of the athletic gut microbiota: a systematic review
title_full_unstemmed Next-generation sequencing of the athletic gut microbiota: a systematic review
title_sort Next-generation sequencing of the athletic gut microbiota: a systematic review
dc.creator.none.fl_str_mv Sabater, Carlos
Iglesias-Gutiérrez, Eduardo
Ruíz García, Lorena
Margolles Barros, Abelardo
author Sabater, Carlos
author_facet Sabater, Carlos
Iglesias-Gutiérrez, Eduardo
Ruíz García, Lorena
Margolles Barros, Abelardo
author_role author
author2 Iglesias-Gutiérrez, Eduardo
Ruíz García, Lorena
Margolles Barros, Abelardo
author2_role author
author
author
dc.contributor.none.fl_str_mv Agencia Estatal de Investigación (España)
Ministerio de Ciencia e Innovación (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Gut microbiome
Athletes
Exercise
Metagenomics
Systematic review
topic Gut microbiome
Athletes
Exercise
Metagenomics
Systematic review
description Aim: There is growing evidence that physical activity modulates gut microbiota composition through complex interactions between diet and microbial species. On the other hand, next-generation sequencing techniques include shotgun metagenomics and 16S amplicon sequencing. These methodologies allow a comprehensive characterisation of microbial communities of athletes from different disciplines as well as non-professional players and sedentary adults exposed to training. This systematic review summarises recent applications of next-generation sequencing to characterise the athletic gut microbiome. Methods: A systematic review of microbiome research was performed to determine the association of microbiota composition profiles with sports performance. Results: Bibliographic analysis revealed the importance of a novel research trend aiming at deciphering the associations between individual microbial species and sports performance. In addition, literature review highlighted the role of butyrate-producing bacteria such as Anaerostipes hadrus, Clostridium bolteae, Faecalibacterium prausnitzii, Roseburia hominis and unidentified species belonging to Clostridiales, Lachnospiraceae and Subdoligranulum species in gut health and sports performance across several disciplines. Interestingly, metabolic activities of Prevotella copri and Veillonella atypica involved in branched amino acid and lactate metabolism may contribute to reducing muscular fatigue. Other microbial metabolic pathways of interest involved in carbohydrate metabolism showed increased proportions in athletes´ metagenomes. Conclusion: Future research will aim at developing personalised nutrition interventions to modulate key species associated with certain components of exercise.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/351091
https://api.elsevier.com/content/abstract/scopus_id/85181440466
url http://hdl.handle.net/10261/351091
https://api.elsevier.com/content/abstract/scopus_id/85181440466
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/AEI//FJC2019-042125-I
The underlying dataset has been published as supplementary material of the article in the publisher platform at https://dx.doi.org/10.20517/mrr.2022.16
https://dx.doi.org/10.20517/mrr.2022.16
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv OAE Publishing
publisher.none.fl_str_mv OAE Publishing
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869411389651550208
score 15,81155

Similares en LA Referencia