Supporting Information: Aspergillus niger ochratoxinase is a highly specific, metal-dependent amidohydrolase suitable for OTA biodetoxification in food and feed

Scheme of the hydrolysis of the amide bond of OTA, SDS-PAGE analysis of recombinant AnOTA from A. niger CBS 513.88, structural comparison of the AnOTA subunit with those from its close structural homologues, structures of the substrates used in our study classified into five families and also those...

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Detalhes bibliográficos
Autores: Sánchez-Arroyo, Ana, Plaza-Vinuesa, Laura, De Las Rivas, Blanca, Mancheño, Jose M., Muñoz, Rosario
Formato: conjunto de datos
Fecha de publicación:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/381760
Acesso em linha:http://hdl.handle.net/10261/381760
Access Level:acceso abierto
Descrição
Resumo:Scheme of the hydrolysis of the amide bond of OTA, SDS-PAGE analysis of recombinant AnOTA from A. niger CBS 513.88, structural comparison of the AnOTA subunit with those from its close structural homologues, structures of the substrates used in our study classified into five families and also those of OTA and 4MF, docking of OTA into the cryoEM 3D structure of the AnOTA homologue enzyme ADH3 from S. acidaminiphila (SaOTA) and comparison with the experimentally determined structure of the mycotoxin, and SDS-PAGE analysis of plant-based beverages containing OTA (5 μM) incubated with AnOTA at 37 °C for 18 h.