A multidisciplinary proposal for a diagnostic algorithm in idiopathic pulmonary fibrosis: the role of transbronchial cryobiopsy

The diagnosis of idiopathic pulmonary fibrosis (IPF) is a complex process that requires the multidisciplinary integration of clinical, radiological, and histological variables. Due to its diagnostic yield, surgical lung biopsy has been the recommended procedure for obtaining samples of lung parenchy...

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Detalles Bibliográficos
Autores: Castillo, Diego, Sánchez-Font, Albert, Pajares, Virginia, Franquet, Tomás, Llatjós, Roger, Sansano, Irene, Sellarés, Jacobo, Centeno, Carmen, Fibla, Juan J., Sánchez, Marcelo, Ramírez, José, Moreno, Amalia, Trujillo-Reyes, Juan Carlos, Barbeta, Enric, Molina-Molina, María, Torrego, Alfons, CRIOMPID
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2020
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/43650
Acceso en línea:http://hdl.handle.net/10230/43650
http://dx.doi.org/10.1016/j.arbres.2019.07.001
Access Level:acceso abierto
Palabra clave:Biopsia pulmonar quirúrgica
Criobiopsia transbronquial
Diagnosis
Diagnóstico
Diffuse interstitial lung disease
Enfermedad pulmonar intersticial difusa
Fibrosis pulmonar idiopática
Idiopathic pulmonary fibrosis
Surgical lung biopsy
Transbronchial cryobiopsy
Descripción
Sumario:The diagnosis of idiopathic pulmonary fibrosis (IPF) is a complex process that requires the multidisciplinary integration of clinical, radiological, and histological variables. Due to its diagnostic yield, surgical lung biopsy has been the recommended procedure for obtaining samples of lung parenchyma, when required. However, given the morbidity and mortality of this technique, alternative techniques which carry a lower risk have been explored. The most important of these is transbronchial cryobiopsy -transbronchial biopsy with a cryoprobe- which is useful for obtaining lung tissue with less comorbidity. Yield may be lower than surgical biopsy, but it is higher than with transbronchial biopsy with standard forceps. This option has been discussed in the recent clinical guidelines for the diagnosis of IPF, but the authors do not go so far as recommend it. The aim of this article, the result of a multidisciplinary discussion forum, is to review current evidence and make proposals for the use of transbronchial cryobiopsy in the diagnosis of IPF.