Role of bifidobacteria on infant health

Bifidobacteria are among the predominant microorganisms during infancy, being a dominant microbial group in the healthy breastfed infant and playing a crucial role in newborns and infant development. Not only the levels of the Bifidobacterium genus but also the profile and quantity of the different...

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Detalles Bibliográficos
Autores: Saturio López, Silvia, Nogacka, Alicja, Alvarado-Jasso, Guadalupe Monserrat, Salazar, Nuria, González de los Reyes-Gavilán, Clara, Gueimonde Fernández, Miguel, Arboleya, Silvia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/264169
Acceso en línea:http://hdl.handle.net/10261/264169
Access Level:acceso abierto
Palabra clave:Bifidobacteria
Gut microbiota
Health
Development
Early life
Infant
Probiotics
Disease
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Descripción
Sumario:Bifidobacteria are among the predominant microorganisms during infancy, being a dominant microbial group in the healthy breastfed infant and playing a crucial role in newborns and infant development. Not only the levels of the Bifidobacterium genus but also the profile and quantity of the different bifidobacterial species have been demonstrated to be of relevance to infant health. Although no definitive proof is available on the causal association, reduced levels of bifidobacteria are perhaps the most frequently observed alteration of the intestinal microbiota in infant diseases. Moreover, Bifidobacterium strains have been extensively studied by their probiotic attributes. This review compiles the available information about bifidobacterial composition and function since the beginning of life, describing different perinatal factors affecting them, and their implications on different health alterations in infancy. In addition, this review gathers exhaustive information about pre‐clinical and clinical studies with Bifidobacterium strains as probiotics in neonates.